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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
SummaryPubMed Citation
Inhibition of human erythrocyte CuZn-SOD assessed as reduction of nitrobluetetrazolium measured for 10 mins by spectrophotometric analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
Inhibition of human Cu-Zn SOD by NBT reduction assay
Assay data:4 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Inhibition of SOD1 in human erythrocytes by spectrophotometry
Inhibition of SOD1 G93A mutant aggregation-induced cytotoxicity in rat PC12 cells incubated for 24 hrs and measured 72 hrs post compound dose by cytotoxicity protection assay
Assay data:18 Active, 8 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of SOD1 G93A mutant aggregation-induced cytotoxicity in rat PC12 cells assessed as cell viability incubated for 24 hrs and measured 72 hrs post compound dose by cytotoxicity protection assay
Assay data:19 Tested
Inhibition of SOD1 G93A mutant aggregation-induced cytotoxicity in human HEK293 cells by cytotoxicity protection assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of SOD1 G93A mutant aggregation-induced cytotoxicity in human HeLa cells by cytotoxicity protection assay
Inhibition of SOD1 G93A mutant aggregation-induced cytotoxicity in human SH-SY5Y cells by cytotoxicity protection assay
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Binding affinity to Superoxide dismutase [Cu-Zn] (unknown origin) at 3.86 10'-5 mol/l after 10 min by UV-Vis spectrophotometric analysis
Assay data:3 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of human Cu-Zn superoxide dismutase assessed as inhibition of NADPH reduction
Assay data:6 Tested
Binding affinity to human GST-SOD1 expressed in Escherichia coli Rosetta at 100 uM in presence of human plasma by reverse phase HPLC analysis
Assay data:7 Tested
Stimulation of SOD activity in Nicotiana tabacum after 3 days
inhibition of CuZn-SOD in human erythrocytes at 125 uM
inhibition of CuZn-SOD in human erythrocytes at 25 uM
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