BioAssay by Target (List) for Gene (Select 7155) - PubChem BioAssay - NCBI

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Select item 787061.

Minimum effective dose required for the inhibition of Escherichia coli gyrase

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:6 Tested

AID:: 78706

Summary PubMed Citation Related BioAssays by Target

Select item 786932.

Antibacterial activity against Escherichia coli DNA gyrase

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:3 Tested

AID:: 78693

Summary PubMed Citation Related BioAssays by Target

Select item 786953.

Gyrase inhibitory activity against Escherichia coli

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:4 Tested

AID:: 78695

Summary PubMed Citation Related BioAssays by Target

Select item 786974.

Inhibition effect on Escherichia coli Wild Type DNA gyrase Supercoiling activity

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78697

Summary PubMed Citation Related BioAssays by Target

Select item 786985.

Inhibition of Escherichia coli Quinolone resistant gyrase Supercoiling activity

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78698

Summary PubMed Citation Related BioAssays by Target

Select item 787016.

Inhibition of supercoiling activity of DNA gyrase in Escherichia coli

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:7 Tested

AID:: 78701

Summary PubMed Citation Related BioAssays by Target

Select item 787027.

Inhibitory concentration against Escherichia coli by Escherichia coli DNA gyrase gel-based supercoil assay

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78702

Summary PubMed Citation Related BioAssays by Target

Select item 787048.

The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:8 Tested

AID:: 78704

Summary PubMed Citation Related BioAssays by Target

Select item 787059.

Inhibition constant against DNA Gyrase isolated from Escherichia coli

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:4 Tested

AID:: 78705

Summary PubMed Citation Related BioAssays by Target

Select item 7869110.

Supercoiling inhibition activity DNA gyrase isolated from Escherichia coli H560

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78691

Summary PubMed Citation Related BioAssays by Target

Select item 7870811.

Inhibitory activity against Escherichia coli DNA gyrase (represented as MNEC)

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:2 Tested

AID:: 78708

Summary PubMed Citation Related BioAssays by Target

Select item 7871012.

Compound was tested for inhibition of target enzyme DNA gyrase obtained from Escherichia coli H560 cells; no data

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78710

Summary PubMed Citation Related BioAssays by Target

Select item 7871113.

In vitro inhibition of supercoiling activity of Escherichia coli DNA gyrase as the ratio of IC50 of Clorobiocin of the compound

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78711

Summary PubMed Citation Related BioAssays by Target

Select item 7871314.

In vitro inhibition of supercoiling activity of Escherichia coli DNA gyrase as the ratio of IC50 of Novobiocin of the compound

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Tested

AID:: 78713

Summary PubMed Citation Related BioAssays by Target

Select item 7871415.

Antibacterial activity against Micrococcus luteus DNA gyrase.

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:4 Tested

AID:: 78714

Summary PubMed Citation Related BioAssays by Target

Select item 7871516.

Inhibition constant against DNA Gyrase isolated from Micrococcus luteus

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:4 Tested

AID:: 78715

Summary PubMed Citation Related BioAssays by Target

Select item 7871617.

Compound was tested for bacterial DNA gyrase activity

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:6 Tested

AID:: 78716

Summary PubMed Citation Related BioAssays by Target

Select item 7871718.

Maximal non-effective concentration against bacterial DNA gyrase

Source:: ChEMBL

Protein Target:: DNA topoisomerase 2-beta

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 78717

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 7854319.

Inhibitory activity against quinolone resistant gyrase in Escherichia coli

Source:: ChEMBL

Protein Targets:: DNA topoisomerase 2-alpha; ...
Total:: 2

Assay data:5 Tested

AID:: 78543

Summary PubMed Citation Related BioAssays by Target

Select item 5723120.

Inhibition of relaxation activities of DNA topoisomerase II with respect to pBR322 DNA

Source:: ChEMBL

Protein Targets:: DNA topoisomerase 2-alpha; ...
Total:: 2

Assay data:1 Tested

AID:: 57231

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (84)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (29)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (79)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
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Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (272)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (267)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (18)
BioAssays deposited by other experimentalists

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