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Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from male (Rvb = 58%)
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
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Inhibition of GPIbalpha-vWF binding assessed as inhibition of ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay
Assay data:8 Tested
Inhibition of GPIbalpha-human vWF binding assessed as decrease in arterial shear-induced platelet adhesion to vWF measuring number of platelets adhered during flow at 100 uM preincubated for 5 mins by parallel plate flow assay with real time imaging microscopy
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of GPIbalpha-human vWF binding assessed as decrease in arterial shear-induced platelet adhesion to vWF measuring number of platelets adhered after flow at 100 uM preincubated for 5 mins by parallel plate flow assay with real time imaging microscopy
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 1 uM after 2 mins by static agglutination assay using washed platelets (Rvb = 66.5%)
Assay data:1 Tested
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 10 uM after 2 mins by static agglutination assay using washed platelets (Rvb = 66.5%)
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets (Rvb = 66.5%)
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 1 uM after 2 mins by static agglutination assay using platelet rich plasma (Rvb = 76.3%)
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 10 uM after 2 mins by static agglutination assay using platelet rich plasma (Rvb = 76.3%)
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using platelet rich plasma (Rvb = 76.3%)
Inhibition of GPIbalpha-human vWF binding assessed as platelet rolling velocity at 100 uM preincubated for 5 mins by parallel plate flow assay with real time imaging microscopy (Rvb = 7.1 um/sec)
Binding affinity to VWF in human A549 cells lysates grown on SILAC media at 10 uM incubated for 1 hr by LC-MS/MS analysis relative to untreated control
Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from female (Rvb = 61.7%)
Inhibition of GPIbalpha-vWF binding assessed as inhibition of ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from male
Inhibition of GPIbalpha-vWF binding assessed as inhibition of ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from female
Inhibition of GPIbalpha-vWF binding assessed as constant shear stress at 120 dynes/cm'2-induced platelet agglutination at 10 uM preincubated for 5 mins by cone and plate rheometer analysis relative to control using male platelet rich plasma (Rvb = 100%)
Assay data:2 Tested
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