BioAssay by Target (List) for Gene (Select 9133) - PubChem BioAssay - NCBI

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Select item 533471.

Inhibition of Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested

AID:: 53347

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 553452.

Inhibition of Cyclin B-cyclin-dependent kinase 1

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:6 Tested

AID:: 55345

Summary PubMed Citation Related BioAssays by Target

Select item 553443.

Inhibition of Cyclin B-cyclin-dependent kinase 1 (not tested)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:2 Tested

AID:: 55344

Summary PubMed Citation Related BioAssays by Target

Select item 553434.

Inhibition of Cyclin B-cyclin-dependent kinase 1

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 55343

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 553425.

Inhibition of Cyclin B-cyclin-dependent kinase 1

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 55342

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 553416.

Inhibition of Cyclin-dependent kinase 1 cyclin B enzyme from starfish oocytes

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:1 Active, 1 Tested

AID:: 55341

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 553407.

Inhibition of Cyclin-dependent kinase 1 enzyme from starfish oocytes

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:1 Tested

AID:: 55340

Summary PubMed Citation Related BioAssays by Target

Select item 533508.

Inhibitory concentration against Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:20 Active, 2 Activity ≤ 1 µM, 23 Tested

AID:: 53350

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 533499.

Inhibitory concentration against CDK1/cyclin B was determined

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested

AID:: 53349

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334810.

Inhibition of cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested

AID:: 53348

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5551711.

Inhibitory activity against cyclin dependent kinase 1-cyclinB from starfish (Marthasterias glacialis) oocytes

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:20 Active, 8 Activity ≤ 1 µM, 38 Tested

AID:: 55517

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334612.

Inhibition of recombinant Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:13 Active, 10 Activity ≤ 1 µM, 13 Tested

AID:: 53346

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334513.

Inhibitory activity against Cyclin-dependent kinase 1-cyclin B using histone as substrate

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 53345

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334414.

Inhibitory activity against Cyclin-dependent kinase 1-cyclin B; NT means not tested

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:8 Tested

AID:: 53344

Summary PubMed Citation Related BioAssays by Target

Select item 5334315.

Inhibitory activity against Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:7 Active, 1 Activity ≤ 1 µM, 11 Tested

AID:: 53343

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334216.

Inhibition of cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 53342

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5334117.

Inhibition of Cyclin-dependent kinase 1-cyclin B at 1 uM

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:3 Tested

AID:: 53341

Summary PubMed Citation Related BioAssays by Target

Select item 5334018.

Inhibition of Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 53340

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5333919.

Inhibition of Cyclin-dependent kinase 1-cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:3 Tested

AID:: 53339

Summary PubMed Citation Related BioAssays by Target

Select item 5554120.

Inhibition of human Cyclin-dependent kinase 1 cyclin B

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 4

Assay data:5 Tested

AID:: 55541

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (67)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (60)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (83)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (134)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (117)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (29)
BioAssays deposited by other experimentalists

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