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Summary of Probe Development Efforts to Identify Inhibitors of Glycogen Synthase Kinase-3 beta (GSK-3b)
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
GSK3beta Surface Plasmon Resonance (SPR) Assay Measured in Biochemical System Using Microfluidics - 2133-08_Inhibitor_Dose_DryPowder_Activity
Assay data:36 Active, 74 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity
Assay data:5 Active, 5 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity
Assay data:22 Active, 27 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 43 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity
Assay data:25 Active, 25 Activity ≤ 1 µM, 92 Tested
Kinome profiling single dose point Measured in Biochemical System Using Plate Reader - 2133-09_Inhibitor_SinglePoint_DryPowder_Activity
Assay data:2 Active, 2 Tested
Human p-Tau and Total Tau ELISA Measured in Cell-Based System Using Plate Reader - 2133-07_Inhibitor_Dose_DryPowder_Activity
Assay data:19 Active, 5 Activity ≤ 1 µM, 24 Tested
GSK3beta Assay at Varied ATP concentrations Measured in Biochemical System Using Plate Reader - 2046-04_Inhibitor_Dose_DryPowder_Activity
Assay data:12 Active, 7 Activity ≤ 1 µM, 15 Tested
CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity
Assay data:36 Active, 3 Activity ≤ 1 µM, 61 Tested
GSK3beta Measured in Biochemical System Using Plate Reader - 2046-01_Inhibitor_Dose_DryPowder_Activity
Assay data:81 Active, 46 Activity ≤ 1 µM, 90 Tested
Inhibition of Human GSK3 beta Activity Measured in Biochemical System Using Microfluidics - 2046-10_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:21 Active, 11 Activity ≤ 1 µM, 24 Tested
Inhibition of Human CDK5 Activity Measured in Biochemical System Using Microfluidics - 2046-12_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:10 Active, 4 Activity ≤ 1 µM, 24 Tested
Inhibition of Human GSK3 alpha Activity Measured in Biochemical System Using Microfluidics - 2046-11_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:18 Active, 6 Activity ≤ 1 µM, 24 Tested
Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity
Assay data:581 Active, 39 Activity ≤ 1 µM, 2198 Tested
Luminescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of ADP-glo Reagents
Assay data:13 Active, 1 Activity ≤ 1 µM, 2198 Tested
Cell-Free Homogeneous Primary HTS to Identify Inhibitors of GSK3beta Activity
Assay data:116 Active, 302503 Tested
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