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AlphaScreen-based biochemical high throughput counterscreen assay to identify compounds that optically interfere with the AlphaScreen
Assay data:356 Active, 4663 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
FRET-based biochemical high throughput dose response assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:77 Active, 5 Activity ≤ 1 µM, 475 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:5861 Active, 646275 Tested
AlphaScreen-based biochemical high throughput dose response counterscreen assay to identify compounds that optically interfere with the AlphaScreen
Assay data:32 Active, 2 Activity ≤ 1 µM, 475 Tested
AlphaScreen-based biochemical high throughput confirmation assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:758 Active, 4663 Tested
AlphaScreen-based biochemical high throughput dose response assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:165 Active, 165 Activity ≤ 1 µM, 475 Tested
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced tyrosinase mRNA expression after 48 hrs by RT-PCR analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced TRP1 mRNA expression after 48 hrs by RT-PCR analysis
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced TRP2 mRNA expression after 48 hrs by RT-PCR analysis
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced tyrosinase protein expression after 48 hrs by Western blotting analysis
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced TRP1 protein expression after 48 hrs by Western blotting analysis
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced TRP2 protein expression after 48 hrs by Western blotting analysis
Inhibition of MITF in mouse B16F10 cells assessed as inhibition of alpha-MSH-induced tyrosinase promoter activity after 24 hrs by luciferase reporter gene assay
Inhibition of MITF binding to M-box region of tyrosinase promoter in alpha-MSH-induced mouse B16F10 cells at 1 uM after 24 hrs by Chromatin immunoprecipitation assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of MITF binding to M-box region of TRP-1 promoter in alpha-MSH-induced mouse B16F10 cells at 1 uM after 24 hrs by Chromatin immunoprecipitation assay
Inhibition of MITF binding to M-box region of TRP-2 promoter in alpha-MSH-induced mouse B16F10 cells at 1 uM after 24 hrs by Chromatin immunoprecipitation assay
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set4
Assay data:103 Active, 13 Activity ≤ 1 µM, 107 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set3
Assay data:87 Active, 1 Activity ≤ 1 µM, 107 Tested
MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:85 Active, 1 Activity ≤ 1 µM, 107 Tested
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:101 Active, 12 Activity ≤ 1 µM, 107 Tested
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