Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Items: 15

Select item 18023931.

VKOR Activity Assay from Article 10.1074/jbc.M113.457119: "VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy."

Source:: BindingDB

Protein Targets:: Vitamin K epoxide reductase complex subunit 1; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1802393

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16338442.

Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested

AID:: 1633844

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 14396773.

Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin K

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:14 Active, 13 Activity ≤ 1 µM, 15 Tested

AID:: 1439677

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 13461384.

Human vitamin K epoxide reductase complex subunit 1 (1.-.-.- Oxidoreductases)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: vitamin K epoxide reductase complex subunit 1 isoform 1 precursor

Assay data:5 Active, 5 Tested

AID:: 1346138

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13460795.

Rat vitamin K epoxide reductase complex subunit 1 (1.-.-.- Oxidoreductases)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: vitamin K epoxide reductase complex subunit 1 precursor

Assay data:1 Active, 1 Tested

AID:: 1346079

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 6702436.

Inhibition of VKORC1

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:4 Tested

AID:: 670243

Summary PubMed Citation Related BioAssays by Target

Select item 2418937.

Inhibitory concentration against beef liver Vitamin K epoxide reductase (vitamin K 2,3-epoxide reductase)

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 241893

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2171508.

Binding affinity for vitamin K 2,3-epoxide

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:1 Tested

AID:: 217150

Summary PubMed Citation Related BioAssays by Target

Select item 2171499.

Binding affinity for vitamin K epoxide reductase

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:1 Tested

AID:: 217149

Summary PubMed Citation Related BioAssays by Target

Select item 21714810.

Vmax value at Vitamin K epoxide reductase; ND-Not Determined

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:5 Tested

AID:: 217148

Summary PubMed Citation Related BioAssays by Target

Select item 21714711.

Vmax value at Vitamin K epoxide reductase

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:7 Tested

AID:: 217147

Summary PubMed Citation Related BioAssays by Target

Select item 21714612.

Km value at Vitamin K epoxide reductase; ND-Not Determined

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:5 Tested

AID:: 217146

Summary PubMed Citation Related BioAssays by Target

Select item 21714513.

Km value at Vitamin K epoxide reductase

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:1 Active, 7 Tested

AID:: 217145

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 21714414.

Apparent kinetic constant of the compound; ND-Not Determined

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:3 Tested

AID:: 217144

Summary PubMed Citation Related BioAssays by Target

Select item 21714315.

Apparent kinetic constant for Vitamin K epoxide reductase

Source:: ChEMBL

Protein Target:: Vitamin K epoxide reductase complex subunit 1

Assay data:1 Active, 8 Tested

AID:: 217143

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (8)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (4)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (9)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (15)
BioAssays extracted from the literature

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