Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of ATX (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of autotaxin (unknown origin)
Inhibition of human recombinant ATX
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Inhibition of human recombinant ATX using ABTS as substrate by absorbance based analysis
Assay data:4 Active, 5 Activity ≤ 1 µM, 5 Tested
ATX Enzyme Activity Inhibition Assay from US Patent US20230295159: "ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF"
Assay data:28 Active, 28 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
ENPP2 Assay from US Patent US11591313: "Inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) and methods of use thereof"
Assay data:10 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibitory Activity on Human ENPP2 from US Patent US11548883: "Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same"
Assay data:80 Active, 80 Activity ≤ 1 µM, 80 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of LPA-mediated ATX activation in human MDA-MB-231 cells assessed as reduction in cell migration incubated for 4 hrs in using18:1 LPC as substrate by Diff-Quick II staining based method
Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysis
Inhibition of ATX stimulated LPA1 internalization in human HeLa-Flp-In cells expressing LPA1-HA assessed as decrease in LPA1 intracellular vesicles under serum starvation condition incubated for 15 mins in presence of 18:1 LPC by confocal imaging analysis relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of LPA-mediated activation of rat ATX
Inhibition of rat ATX by Michaelis-Menten analysis
Inhibition of rat ATX lysoPLD activity assessed as residual activity using 20:0 LPC as substrate measured after 60 mins by HVA fluorescence based analysis relative to control
Inhibition of rat ATX lysoPLD activity assessed as residual activity using 18:1 LPC as substrate measured after 60 mins by HVA fluorescence based analysis relative to control
Inhibition of rat ATX lysoPLD activity assessed as residual activity using 16:0 LPC as substrate measured after 60 mins by HVA fluorescence based analysis relative to control
Inhibition of rat ATX lysoPLD activity assessed as residual activity using 14:0 LPC as substrate measured after 60 mins by HVA fluorescence based analysis relative to control
Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 20:0 LPC as substrate measured after 60 mins by HVA fluorescence based analysis
Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 18:1 LPC as substrate measured after 60 mins by HVA fluorescence based analysis
Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 16:0 LPC as substrate measured after 60 mins by HVA fluorescence based analysis
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on