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Affinity Biochemical interaction (Prostanoid receptor binding assay) EUB0000334a PTGDR2
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Affinity Biochemical interaction (Prostanoid receptor binding assay) EUB0000297b PTGDR2
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity On-target Cellular interaction (cAMP functional assay in HEK-hCRTH2 cells) EUB0000334a PTGDR2
Assay data:1 Tested
SummaryRelated BioAssays by Target
Affinity On-target Cellular interaction (cAMP functional assay in HEK-hCRTH2 cells) EUB0000297b PTGDR2
Biological Activity Assay from US Patent US10800765: "Indole derivative used as CRTH2 inhibitor"
Assay data:53 Active, 62 Activity ≤ 1 µM, 62 Tested
Radioligand Binding Assay from US Patent US9290454: "Substituted isoquinolines as CRTH2 receptor modulators"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
Radioligand Displacement Assay from US Patent US9255090: "Heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators"
Assay data:432 Active, 33 Activity ≤ 1 nM, 432 Activity ≤ 1 µM, 432 Tested
Radioligand Binding Assay from US Patent US9206164: "Pyrazole compounds as CRTH2 antagonists"
Assay data:109 Active, 28 Activity ≤ 1 nM, 109 Activity ≤ 1 µM, 109 Tested
Radioligand Displacement Assay from US Patent US9169270: "1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators"
Assay data:120 Active, 11 Activity ≤ 1 nM, 120 Activity ≤ 1 µM, 120 Tested
Radioligand Displacement Assay from US Patent US9096595: "7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators"
Assay data:51 Active, 10 Activity ≤ 1 nM, 51 Activity ≤ 1 µM, 51 Tested
Fluorometric Imaging Plate Reader (FLIPR) Assay from US Patent US9000044: "Substituted naphthylacetic acids"
Assay data:54 Active, 12 Activity ≤ 1 nM, 53 Activity ≤ 1 µM, 54 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Binding Assay from US Patent US9000044: "Substituted naphthylacetic acids"
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
Radioligand Binding Assay from US Patent US8796280: "2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors"
Assay data:46 Active, 11 Activity ≤ 1 µM, 46 Tested
Radioligand Binding Assay from US Patent US8791272: "Pyrazole compounds as CRTH2 antagonists"
Assay data:214 Active, 33 Activity ≤ 1 nM, 207 Activity ≤ 1 µM, 214 Tested
Radioligand Binding Assay from US Patent US8759386: "Pyrazole compounds as CRTH2 antagonists"
Assay data:59 Active, 47 Activity ≤ 1 nM, 59 Activity ≤ 1 µM, 59 Tested
Biological Assays from US Patent US8697869: "3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators"
Assay data:56 Active, 56 Activity ≤ 1 µM, 56 Tested
Calcium Flux Assay from US Patent US8691993: "Piperidinyl naphthylacetic acids"
Assay data:13 Active, 10 Activity ≤ 1 µM, 13 Tested
Receptor Binding Assay from US Patent US8623903: "Indolecarboxylic acid derivative having PGD2 receptor antagonistic activity"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
Radioligand Binding Assay from US Patent US8536158: "Compounds having CRTH2 antagonist activity"
Assay data:8 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Radioligand Binding Assay from Article 10.1021/jm701383e: "Discovery of a New Class of Potent, Selective, and Orally Bioavailable CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases."
Assay data:28 Active, 19 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
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