Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of Plasmodium falciparum LAP
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Plasmodium falciparum leucine aminopeptidase
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Plasmodium falciparum M17 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay
Assay data:14 Active, 12 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3)
Assay data:6 Active, 14 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2)
Assay data:8 Active, 10 Tested
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2)
Assay data:18 Active, 9 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of PFM1AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2)
Assay data:4 Active, 8 Tested
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP)
Assay data:17 Active, 1 Activity ≤ 1 µM, 31 Tested
Counterscreen for inhibitors of PFM1AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP)
Assay data:17 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP)
Assay data:21 Active, 63 Tested
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 harboring tPfAP-M17 gene at 0.1 uM using Leu-AMC as a substrate by spectrophotometer in presence of 1 nM CoCl2
Assay data:5 Tested
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 harboring tPfAP-M17 gene at 10 uM using Leu-AMC as a substrate by spectrophotometer in presence of 1 nM CoCl2
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 at 0.1 uM using Leu-AMC as a substrate by spectrophotometer in presence of 1 nM CoCl2
Assay data:13 Tested
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 at 10 uM using Leu-AMC as a substrate by spectrophotometer in presence of 1 nM CoCl2
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 at 0.1 uM using Leu-AMC as a substrate by spectrophotometer
Inhibition of leucyl aminopeptidase activity in Plasmodium falciparum 3D7 at 10 uM using Leu-AMC as a substrate by spectrophotometer
Assay data:33 Tested
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M7 Leucine Aminopeptidase (PfM17LAP): fluorescence-based assay to identify inhibitors of rPfM17LAP
Assay data:16 Active, 59 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M7 Leucine Aminopeptidase (PfM17LAP): fluorescence-based biochemical assay to identify inhibitors of malaria cell lysate
Assay data:17 Active, 52 Tested
Summary of the probe development effort to identify inhibitors of the Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17AAP)
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on