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Selectivity interaction (Human bromodomain panel (DSF assay)) EUB0000233b ATAD2B
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (BROMOscan) EUB0001074a ATAD2B
Selectivity interaction (Bromodomain panel (DSF asssay)) EUB0000270b ATAD2B
Inhibition of ATAD2B (unknown origin) assessed as remaining activity
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to human partial length ATAD2B (Q955 to R1082 residues) expressed in bacterial expression system by BROMOscan assay
Assay data:4 Tested
Binding affinity to N-terminal His-TEV-tagged human ATAD2B transfected in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 100 uM by SYPRO orange dye based differential scanning fluorimetry analysis
Binding affinity to human ATAD2B bromodomain assessed as dissociation constant by BROMOscan method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to human ATAD2B bromodomain assessed as residual activity at 300 nM by BROMOscan method relative to control
Binding affinity to human ATAD2B assessed as dissociation constant up to 1 uM by BROMOscan assay
Assay data:2 Tested
ATAD2B DiscoverX BROMOscan
Inhibition of human ATAD2B (Q955 to R1082 residues) at 10 uM by DiscoverX assay relative to control
Binding affinity to N-terminal GST tagged human ATAD2B short form expressed in Escherichia coli by ITC analysis
Assay data:7 Tested
Binding affinity to N-terminal GST tagged human ATAD2B (953-1085 residues) expressed in Escherichia coli by ITC analysis
Assay data:2 Active, 1 Activity ≤ 1 µM, 20 Tested
Thermal Shift Assay. Domain start/stop: M966-G1100
Assay data:10 Tested
Assay data:14 Tested
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