Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
PROTAC activity at VHL/HiBit-tagged BRD7 in HEK293 cells assessed as BRD7 protein degradation pre-incubated with endurazine for 2.5 hrs followed by compound addition and measured after 24 hrs by live cell kinetics assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as maximal degradation by Western blot analysis relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 100 nM incubated for 48 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 10 nM incubated for 48 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as degradation of BRD7 protein incubated for 8 hrs by Western blot analysis
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 nM incubated for 2 hrs by Western blot analysis relative to control
Assay data:2 Tested
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 10 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 100 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 10000 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 0.1 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 10 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 100 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at CRBN/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 uM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at CRBN/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 uM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 uM incubated for 8 hrs by Western blot analysis relative to control
Assay data:3 Tested
PROTAC activity at VHL/BRD7 in human Ri-1 cells assessed as remaining BRD7 protein level at 1 uM incubated for 2 hrs by Western blot analysis relative to control
Assay data:20 Tested
PROTAC activity at VHL/BRD7 in human HeLa cells assessed as protein degradation at 1 uM incubated for 16 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD7 in human HeLa cells assessed as protein degradation at 1 uM incubated for 4 hrs by Western blot analysis relative to control
PROTAC activity at DCAF15/BRD7 in human HeLa cells assessed as remaining BRD7 protein level at 1 uM incubated for 16 hrs by Western blot analysis relative to control
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on