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PRKCA Invitrogen Lab (UK) kinase screen (BI)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of PKCa (unknown origin) at 10 uM by biochemical hotspot kinase assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of PKCB (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PKC (unknown origin) using acetylated myelin basic protein (4 to 14 residues) as substrate incubated for [gamma-32P]-ATP incubated for 5 mins by scintillation counter analysis
Activation of PKC in human THP-1 cells assessed as increase in ERK phosphorylation at 100 nM incubated for 15 mins by immunoblotting analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of PKC in human THP-1 cells assessed as increase in ERK phosphorylation at 0.1 to 10 uM incubated for 15 mins by immunoblotting analysis
Assay data:3 Tested
Activation of PKC in human THP-1 cells assessed as increase in ERK phosphorylation at 10 uM pretreated with PMA for 24 hrs followed by compound addition and measured after 15 mins by immunoblotting analysis
Activation of PKC in human THP-1 cells assessed as increase in ERK phosphorylation incubated for 15 mins by immunoblotting analysis
Assay data:2 Tested
Inhibition of PKC theta type (unknown origin) by Ambit kinase assay
Assay data:4 Tested
Inhibition of PRKCD (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of PKCtheta (unknown origin)
Inhibition of [3H]-PDBu binding to PKCdelta C1B domain (unknown origin) by competitive binding assay
Assay data:4 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of PKC (unknown origin)
Inhibition of PKCalpha (unknown origin) at 1000 nM relative to control
Inhibition of human partial length TPKCtheta (L350/S706) expressed in bacterial system at 1 uM by KINOMEscan analysis relative to control
Inhibition of PKCa (unknown origin) at 25 nM relative to control
Assay data:6 Tested
Inhibition of Protein kinase C (unknown origin)
Assay data:3 Active, 1 Activity ≤ 1 µM, 6 Tested
Inhibition of human PKC
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