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Selectivity interaction (Eurofins CEREP Diversity Profile (receptors and ion channels)) EUB0000279b PPARG
Assay data:1 Tested
SummaryRelated BioAssays by Target
Agonist activity in the Eurofins SafetyScreen44 (BI) against PPARG/H AG by Radioactive Assay (Old_Cerep_35)
Agonist activity at human PPAR gamma transfected in African green monkey COS-7 cells co-transfected with CMX-Gal4 fused hPPARgamma/TK-MH100x4-Luc/renilla luciferase at 10 uM incubated for 24 hrs by Dual-Glo luciferase assay
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at human PPAR gamma transfected in African green monkey COS-7 cells co-transfected with CMX-Gal4 fused hPPARgamma/TK-MH100x4-Luc/renilla luciferase assessed as fold increase in luciferase activity at 10 uM incubated for 24 hrs by Dual-Glo luciferase assay
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human PPAR alpha transfected in African green monkey COS-7 cells co-transfected with CMX-Gal4 fused hPPARalpha/TK-MH100x4-Luc/renilla luciferase assessed as fold increase in luciferase activity at 10 uM incubated for 24 hrs by Dual-Glo luciferase assay
Assay data:7 Tested
Agonist activity at PPARdelta LBD (unknown origin) transiently transfected in HEK293T cells at 1 uM incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo luciferase assay
Agonist activity at PPARgamma LBD (unknown origin) transiently transfected in HEK293T cells at 1 uM incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo luciferase assay
Agonist activity at PPARalpha LBD (unknown origin) transiently transfected in HEK293T cells at 1 uM incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo luciferase assay
Activation of PPARalpha (unknown origin) expressed in human HepG2 cells assessed as fold change at 1.47 ug/ml incubated for 24 hrs by luciferase assay
Activation of PPARalpha (unknown origin) expressed in human HepG2 cells assessed as fold change at 12.5 to 50 ug/ml incubated for 24 hrs by luciferase assay
Activation of PPAR gamma in H2O2 induced human SH-SY5Y cells assessed as increase in superoxide dismutase 1 mRNA expression at 10 uM incubated for 6 hrs by qPCR analysis
Assay data:1 Active, 1 Tested
Activation of PPARgamma in H2O2 induced human SH-SY5Y cells assessed as increase in superoxide dismutase 1 mRNA expression at 0.001 uM incubated for 6 hrs by qPCR analysis
Assay data:3 Active, 3 Tested
Activation of PPARgamma in human SH-SY5Y cells assessed as increase in superoxide dismutase 1 mRNA expression at 0.001 uM incubated for 6 hrs by qPCR analysis
Activation of PPARgamma in human SH-SY5Y cells assessed as increase in Nrf2 mRNA expression level at 0.001 uM incubated for 6 hrs by qPCR analysis
Activation of PPARgamma in H2O2 induced human SH-SY5Y cells assessed as increase in glutathione peroxidase 1 mRNA expression incubated for 6 hrs by qPCR analysis
Activation of PPARgamma in human SH-SY5Y cells assessed as increase in glutathione peroxidase 1 mRNA expression incubated for 6 hrs by qPCR analysis
Activation of PPARgamma in H2O2 induced human SH-SY5Y cells assessed as increase in catalase mRNA expression level incubated for 6 hrs by qPCR analysis
Assay data:2 Active, 2 Tested
Activation of PPARgamma in human SH-SY5Y cells assessed as increase in catalase mRNA expression level incubated for 6 hrs by qPCR analysis
Activation of PPARgamma in H2O2 induced human SH-SY5Y cells assessed as increase in PPARgamma nucleus translocation incubated for 6 hrs by Western blot analysis
Assay data:3 Tested
Activation of PPARgamma in human SH-SY5Y cells assessed as increase in PPARgamma nucleus translocation at 0.001 uM incubated for 6 hrs by Western blot analysis
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