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Surface Plasmon Resonance Assay from US Patent US20240197735: "METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST"
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Measurement of FXIa Inhibition from US Patent US20240174633: "CRYSTALLINE FORMS OF (4S)-24-CHLORO-4-ETHYL-73-FLUORO-35-METHOXY-32,5-DIOXO-14-(TRIFLUORO-METHYL)-32H-6-AZA-3(4,1)-PYRIDINA-1(1)-[1,2,3]TRIAZOLA-2(1,2),7(1)-DIBENZENAHEPTAPHANE-74-CARBOXAMIDE"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Kinase Assay from US Patent US20240174621: "METHYLQUINAZOLINONE DERIVATIVES"
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
HCK Kinase Assay from US Patent US11963960: "Compounds for treating or inhibiting recurrence of acute myeloid leukemia"
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
LYN A Invitrogen Lab (UK) kinase screen (BI)
LCK_CE Eurofins SafetyScreen44 (BI)
Inhibition of LCK (unknown origin) upto 10000 nM
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of LYN (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of LCK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
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