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CLK3 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of CLK2 (unknown origin) at 1 uM relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis
Assay data:31 Active, 11 Activity ≤ 1 µM, 56 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human CLK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis
Assay data:46 Active, 1 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 56 Tested
Inhibition of human CLK2 measured by DSF assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CLK3 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CLK2 (unknown origin)
Inhibition of human CLK3 at 12 degree celcius
Inhibition of human CLK3 administered orally
Inhibition of human CLK2 administered orally
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human CLK3 assessed as residual activity at 3 uM
Inhibition of human CLK2 by NanoBRET assay
Inhibition of human CLK2
Assay data:28 Active, 1 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 28 Tested
Inhibition of human CLK2 mediated phosphorylation of SRSF4 in hMSCs assessed by TCF/LEF reporter assay
Inhibition of human CLK2 mediated phosphorylation of SRSF5 in hMSCs assessed by TCF/LEF reporter assay
Inhibition of human CLK2 mediated phosphorylation of SRSF6 in hMSCs assessed by TCF/LEF reporter assay
Inhibition of Human CLK2 mediated phosphorylation of SRSF4 in human chondrocytes assessed by TCF/LEF reporter assay
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