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Antagonist activity at NR2C1 (unknown origin) at 1 uM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inverse agonist activity at NR2C1 (unknown origin) at 1 uM
Agonist activity at NR2C1 (unknown origin) at 1 uM
Inhibition of COT1 (unknown origin)
Inhibition of COT1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay
Assay data:3 Tested
Luminescence-based cell-based late stage dose response assay to identify inhibitors of COUP-TFII (NR2F2) (Round 000)
Assay data:32 Active, 4 Activity ≤ 1 µM, 33 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2)
Assay data:173 Active, 15 Activity ≤ 1 µM, 232 Tested
Inhibition of human recombinant COT1 by radiometric kinase assay
Luminescence-based cell-based high throughput confirmation assay to identify inhibitors of COUP-TFII (NR2F2)
Assay data:1133 Active, 2497 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Summary of a probe development effort to identify inhibitors of COUP-TFII (NR2F2)
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2)
Assay data:2610 Active, 370276 Tested
Effect on EAR2(NR2F6) dependent reporter activity in HEK293 cells at 20 uM
Assay data:2 Tested
Effect on TFCOUP2(NR2F2) dependent reporter activity in HEK293 cells at 20 uM
Effect on TFCOUP1(NR2F1) dependent reporter activity in HEK293 cells at 20 uM
Effect on TR2(NR2C1) dependent reporter activity in HEK293 cells at 20 uM
Late stage assay provider results from the probe development effort to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors
Assay data:1 Active, 1 Tested
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors.
Assay data:14 Active, 14 Tested
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