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Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Glutamate, NMDA, Glycine Eurofins Panlabs panel
Glutamate, NMDA, Agonism Eurofins Panlabs panel
NMDA/R Eurofins SafetyScreen44 (BI)
Antagonist activity at NMDA receptor (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cells
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
Positive allosteric modulator activity at NMDA receptor in rat Hippocampal neurone
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Positive allosteric modulation of GluN1/GluN2B receptor (unknown origin) stably expressed in HEK293 cells assessed as glutamate/glycine induced increase in intracellular calcium level at 10 uM incubated for 30 mins followed by addition of glutamate/glycine by Ca2+ influx assay
Assay data:3 Active, 4 Tested
Antagonist activity at NMDA receptor NR2B subunit (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Displacement of [3H]ifenprodyl from NMDA receptor (unknown origin)
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
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