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Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS expression at 3 uM in presence of Y1R antagonist BIIE-0246 by Western blotting analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production at 3 uM measured after 24 hrs in presence of Y1R antagonist BIIE-0246 by Griess method
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS expression at 3 uM in presence of Y1R antagonist BIBP3226 by Western blotting analysis
Assay data:1 Tested
SummaryPubMed Citation
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production at 3 uM measured after 24 hrs in presence of Y1R antagonist BIBP3226 by Griess method
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS expression at 3 uM by Western blotting analysis
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production at 3 uM measured after 24 hrs by Griess method
Effect on LPS-induced inflammasome activation in mouse C8D1A cells assessed as reduction in caspase 1 protein level at 0.75 to 3 uM by Western blotting analysis
Effect on LPS-induced inflammasome activation in mouse C8D1A cells assessed as reduction in NLRP3 protein level at 0.75 to 3 uM by Western blotting analysis
Inhibition of NFkappaB p65 phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis
Inhibition of IkappaBalpha phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of IKKalpha/beta phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced GFAP production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by DMI-8 microscopy
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced TNFalpha mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-1beta mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-6 mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced TNFalpha production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-1beta production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-6 production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced ROS production measured after 24 hrs by fluorescent CM-H2DCFDA based flow cytometry
Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS production by Western blotting analysis
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