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Antitumor activity against human PC-3 cells xenografted in mouse assessed as increase in total protein level at 5.2 mg/kg,ip administration (Rvb = 4.01 +/- 0.27 g/dl)
Assay data:2 Tested
SummaryPubMed Citation
Antitumor activity against human PC-3 cells xenografted in mouse assessed as decrease in AST level at 5.2 mg/kg,ip administration (Rvb = 85.38 +/- 1.59 I/U)
Antitumor activity against human PC-3 cells xenografted in mouse assessed as decrease in ALT level at 5.2 mg/kg,ip administration (Rvb = 81.25 +/- 1.69 I/U)
Antitumor activity against human PC-3 cells xenografted in mouse assessed as decrease in WBC count at 5.2 mg/kg,ip administration (Rvb = 4.98 +/- 0.87 10^3/microL)
Antitumor activity against human PC-3 cells xenografted in mouse assessed as increase in RBC count at 5.2 mg/kg,ip administration (Rvb = 2.34 +/- 0.57 10^6/microL)
Antitumor activity against human PC-3 cells xenografted in mouse assessed as increase in hemoglobin level at 5.2 mg/kg,ip administration (Rvb = 2.94 +/- 0.54 g/dl)
Antitumor activity against human PC-3 cells xenografted in mouse assessed as tumor growth inhibition at 5.2 mg/kg,ip administration
Assay data:1 Tested
Antitumor activity against human PC-3 cells xenografted in mouse assessed as decrease in tumor volume at 5.2 mg/kg,ip administration
Antitumor activity against human PC-3 cells xenografted in mouse assessed as decrease in tumor mass at 5.2 mg/kg,ip administration
Inhibition of PIM-1 (unknown origin)
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Cytotoxicity against human RWPE2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Assay data:6 Tested
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Assay data:8 Active, 1 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Assay data:9 Active, 1 Activity ≤ 1 µM, 14 Tested
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Assay data:10 Active, 5 Activity ≤ 1 µM, 14 Tested
Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assay
Assay data:49 Active, 81 Activity ≤ 1 µM, 90 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of FGFR-1 (unknown origin) incubated for 60 mins in presence of ATP by ADP-Glo kinase assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of GSK3beta (unknown origin) incubated for 20 mins in presence of 33P-ATP
Assay data:9 Active, 3 Activity ≤ 1 µM, 10 Tested
Inhibition of JNK1 (unknown origin) incubated for 20 mins in presence of 33P-ATP
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of JNK2 (unknown origin) incubated for 20 mins in presence of 33P-ATP
Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting method
Assay data:10 Active, 10 Activity ≤ 1 µM, 11 Tested
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