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p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: Summary
Assay data:70 Active, 12 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
p53 small molecule agonists, cell-based qHTS assay: Summary
Assay data:212 Active, 41 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Assay data:103 Active, 14 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay
Assay data:87 Active, 5 Activity ≤ 1 nM, 180 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter screen
Assay data:213 Active, 2 Activity ≤ 1 nM, 241 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS cell viability counter screen
Assay data:214 Active, 153 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS cell viability counter screen
Assay data:300 Active, 138 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Assay data:27 Active, 44 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Assay data:43 Active, 55 Activity ≤ 1 µM, 9667 Tested
HTS to identify compounds that affect the blood-brain barrier permeability in vitro
Assay data:419 Active, 1260 Tested
SummaryCompounds, Active
Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy
Assay data:34 Active, 15 Activity ≤ 1 µM, 906 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy
Assay data:13 Active, 8 Activity ≤ 1 µM, 927 Tested
Binding affinity towards human SLC6A4 in an in vitro assay with cellular components measured by scintillation counting
Assay data:99 Active, 36 Activity ≤ 1 µM, 927 Tested
Binding affinity towards human SLC6A3 in an in vitro assay with cellular components measured by scintillation counting
Assay data:128 Active, 38 Activity ≤ 1 µM, 927 Tested
Binding affinity towards human SLC6A2 in an in vitro assay with cellular components measured by scintillation counting
Assay data:137 Active, 27 Activity ≤ 1 µM, 927 Tested
Compound was evaluated for inhibition of human PTGS1 in an in vitro cell free assay measured by fluorescence method
Assay data:80 Active, 33 Activity ≤ 1 µM, 924 Tested
Compound was evaluated for inhibition of human PTGS1 in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:96 Active, 35 Activity ≤ 1 µM, 927 Tested
Binding affinity towards human PGR in an in vitro assay with cellular components measured by scintillation counting
Assay data:87 Active, 51 Activity ≤ 1 µM, 927 Tested
Compound was evaluated for inhibition of human PDE4A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:46 Active, 10 Activity ≤ 1 µM, 927 Tested
Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:15 Active, 6 Activity ≤ 1 µM, 927 Tested
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