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Inhibition of Plasmodium falciparum 3D7 Prolyl-tRNA synthetase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Therapeutic index, ratio of IC50 for mouse J774 cells to IC50 chloroquine-resistant Plasmodium falciparum W2
Assay data:1 Tested
SummaryPubMed Citation
Antimalarial activity against Plasmodium berghei infected in po dosed mouse erythrocyte administered qd for 8 days by Giemsa staining based microscopic analysis
Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 by [3H]-hypoxanthine incorporation assay
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Therapeutic index, ratio of IC50 for mouse/rat NG108 cells to IC50 chloroquine-resistant Plasmodium falciparum W2
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