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Inhibitor identification of human QSOX1 enzyme: high-throughput screening using HyperBlu(TM) assay
Assay data:979 Active, 1265 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Mouse Kir2.1 (Inwardly rectifying potassium channels)
Assay data:9 Active, 9 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Human Kir2.3 (Inwardly rectifying potassium channels)
Assay data:12 Active, 12 Tested
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
Inhibition of [3H]putrescine transport by the compound was evaluated in T-47D human breast cancer cells
Assay data:11 Active, 7 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Michaelis-Menten constant of compound was determined at MDA-MB-231 cell line mediated by polyamine transporter
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of [3H]spermidine transport into MDA-MB-231 (human breast cancer) cells.
Assay data:11 Active, 11 Activity ≤ 1 µM, 12 Tested
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
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