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Antibiofilm activity against Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant preformed biofilms assessed as reduction in biofilm bacterial count at 340 uM preincubated for 24 hrs under non-shaking condition followed by second incubation for 1 hr after compound washout and subsequent compound addition and measured after 1 hr incubation under non-shaking condition by crystal-violet staining based assay
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of biofilm formation in eGFP-fused Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant at 340 uM after 24 hrs under shaking condition by confocal laser scanning microscopy
Induction of structured biofilm formation in eGFP-fused Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant at 20 uM after 24 hrs under shaking condition by confocal laser scanning microscopy
Induction of tendril formation in Pseudomonas aeruginosa PAO1 at > 85 uM after 24 hrs
Assay data:1 Active, 1 Tested
Induction of swarming motility of wild-type Pseudomonas aeruginosa PAO1 at 50 uM after 24 hrs
Induction of tendril formation in Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant at 5 to 100 uM after 24 hrs
Induction of swarming motility of Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant at 5 to 100 uM after 24 hrs
Assay data:1 Active, 3 Tested
Induction of biofilm formation in Pseudomonas aeruginosa PW6886 harboring rhlA-E08::ISphoA/hah mutant at 20 to 170 uM after 24 hrs under non-shaking condition by crystal-violet staining based assay
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