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Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay
Assay data:1 Active, 11 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Stability in DMSO at 10 mM shaken gently at 25 degC exposed toN2 atmosphere assessed as compound degradation measured over 9 hrs by HPLC analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, Active
Stability in saturated N2 atmosphere assessed as drug degradation by NMR and LC-MS/MS analysis
Inhibition of APOBEC3A (unknown origin) by fluorescence-based ssDNA C-to-U deaminase assay
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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