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Binding affinity to NMDA receptor (unknown origin)
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human mGluR7 expressed in CHO cells assessed as change in extracellular impedance incubated for 40 mins by CellKey impedance assay
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Membrane potential based transport assay for SLC1A3 using HEK293 JumpIn SLC1A3 OE cells
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Impedance-based phenotypic for SLC1A3 using HEK JumpIn SLC1A3 OE cells
Assay data:6 Active, 1 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Displacement of [3H]KA from rat brain cortical membranes Kainate receptor incubated for 30 mins by equilibrium binding assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Displacement of [3H]AMPA from rat brain cortical membranes AMPA receptor incubated for 30 mins by equilibrium binding assay
Displacement of [3H]CPP from rat brain cortical membranes NMDA receptor incubated for 30 mins by equilibrium binding assay
Agonist activity at GluA4 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 90 secs in presence of cyclothiazide by Fluo4-AM dye-based fluorescence assay
Assay data:1 Active, 6 Tested
Displacement of [3H]CGP39653 from NMDA receptor in rat brain synaptic cortical membranes after 60 mins by scintillation counting method
Assay data:2 Active, 1 Activity ≤ 1 µM, 8 Tested
Displacement of [3H]KA from KA receptor in rat brain synaptic cortical membranes after 60 mins by scintillation counting method
Assay data:2 Active, 2 Activity ≤ 1 µM, 8 Tested
Displacement of [3H]AMPA from AMPA receptor in rat brain synaptic cortical membranes after 30 mins by scintillation counting method
Assay data:4 Active, 2 Activity ≤ 1 µM, 8 Tested
Activation of human CA1 by stopped-flow CO2 hydration assay
Assay data:14 Active, 8 Activity ≤ 1 µM, 24 Tested
Inhibitor identification of human QSOX1 enzyme: high-throughput screening using HyperBlu(TM) assay
Assay data:979 Active, 1265 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Inhibitor identification of human QSOX1 enzyme: high-throughput screening using ROS-Glo(TM) assay
Assay data:750 Active, 1265 Tested
Rat mGlu2 receptor (Metabotropic glutamate receptors)
Assay data:29 Active, 29 Tested
Human mGlu4 receptor (Metabotropic glutamate receptors)
Assay data:26 Active, 26 Tested
Rat mGlu4 receptor (Metabotropic glutamate receptors)
Assay data:13 Active, 13 Tested
Human mGlu8 receptor (Metabotropic glutamate receptors)
Assay data:14 Active, 14 Tested
Rat mGlu1 receptor (Metabotropic glutamate receptors)
Assay data:61 Active, 61 Tested
Human mGlu6 receptor (Metabotropic glutamate receptors)
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