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HTS to identify compounds that affect the blood-brain barrier permeability in vitro
Assay data:419 Active, 1260 Tested
SummaryCompounds, Active
Human Ether-a-go-go-Related Gene (hERG) channel small molecule antagonists: fluorescence cell-based qHTS assay
Assay data:704 Active, 81 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibitor identification of human QSOX1 enzyme: high-throughput screening using HyperBlu(TM) assay
Assay data:979 Active, 1265 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Mouse Constitutive androstane receptor (1I. Vitamin D receptor-like receptors)
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 16 hour
Assay data:413 Active, 35 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 8 hour
Assay data:327 Active, 30 Activity ≤ 1 µM, 9667 Tested
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 32 hour
Assay data:713 Active, 71 Activity ≤ 1 µM, 9667 Tested
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 24 hour
Assay data:588 Active, 51 Activity ≤ 1 µM, 9667 Tested
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 40 hour
Assay data:848 Active, 77 Activity ≤ 1 µM, 9667 Tested
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line
Assay data:2501 Active, 1 Activity ≤ 1 nM, 348 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary
Assay data:1260 Active, 187 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay for small molecule disruptors of the mitochondrial membrane potential
Assay data:1817 Active, 1 Activity ≤ 1 nM, 393 Activity ≤ 1 µM, 10486 Tested
Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format
Assay data:180 Active, 6 Activity ≤ 1 µM, 373 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex
Assay data:408 Active, 95 Activity ≤ 1 µM, 1728 Tested
qHTS assay for small molecule agonists of estrogen receptor alpha signaling
Assay data:88 Active, 2 Activity ≤ 1 nM, 43 Activity ≤ 1 µM, 2858 Tested
Primary cell-based high-throughput screening for identification of compounds that allosterically activate MrgX1 receptor signaling
Assay data:1933 Active, 306595 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
uHTS identification of antagonists of the CRF-binding protein and CRF-R2 receptor complex
Assay data:2056 Active, 349168 Tested
qHTS for inhibitors of binding or entry into cells for Marburg Virus
Assay data:5375 Active, 30 Activity ≤ 1 nM, 10501 Activity ≤ 1 µM, 301745 Tested
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