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Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists, luciferase reporter gene qHTS assay in human keratinocytes: Summary
Assay data:1038 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Inhibition of human myc-His6-tagged zDHHC2 expressed in HEK293T cells using 5-FAM-GTQGCMGLPCVVM-COOH as substrate preincubated for 30 mins followed by substrate addition and measured at 1 min interval for 2 hrs in presence of palmitoyl-CoA by fluorescence polarization assay
Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of human myc-His6-tagged zDHHC20 expressed in HEK293T cells using 5-FAM-GTQGCMGLPCVVM-COOH as substrate preincubated for 1 hr followed by substrate addition and measured at 1 min interval for 2 hrs in presence of palmitoyl-CoA by fluorescence polarization assay
Assay data:7 Active, 8 Tested
SummaryCompounds, ActivePubMed Citation
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HepG2 cells - 32 hour
Assay data:900 Active, 77 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HepG2 cells - 40 hour
Assay data:1023 Active, 88 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the hypoxia (HIF-1) signaling pathway - cell viability counter screen
Assay data:617 Active, 94 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen
Assay data:328 Active, 5 Activity ≤ 1 nM, 337 Activity ≤ 1 µM, 9315 Tested
qHTS assay to identify small molecule agonists of the NFkB signaling pathway - cell viability counter screen
Assay data:296 Active, 4 Activity ≤ 1 nM, 141 Activity ≤ 1 µM, 9315 Tested
qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary
Assay data:118 Active, 3 Activity ≤ 1 µM, 9305 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary
Assay data:112 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen
Assay data:526 Active, 3 Activity ≤ 1 nM, 525 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway
Assay data:32 Active, 1 Activity ≤ 1 nM, 79 Activity ≤ 1 µM, 9305 Tested
qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen
Assay data:410 Active, 2 Activity ≤ 1 nM, 209 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen
Assay data:524 Active, 353 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary
Assay data:277 Active, 1 Activity ≤ 1 nM, 62 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary
Assay data:426 Active, 1 Activity ≤ 1 nM, 201 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen
Assay data:1423 Active, 3 Activity ≤ 1 nM, 263 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary
Assay data:670 Active, 220 Activity ≤ 1 µM, 10486 Tested
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line
Assay data:2493 Active, 2 Activity ≤ 1 nM, 413 Activity ≤ 1 µM, 10486 Tested
qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary
Assay data:1260 Active, 187 Activity ≤ 1 µM, 10486 Tested
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