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Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists, luciferase reporter gene qHTS assay in human keratinocytes: Summary
Assay data:1038 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library: Summary
Assay data:309 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library: Summary
Assay data:390 Active, 9667 Tested
qHTS assay to identify small molecule HDAC inhibitors: Summary
Assay data:421 Active, 16 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway in the presence of an antagonist
Assay data:382 Active, 2 Activity ≤ 1 nM, 175 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library
Assay data:318 Active, 199 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library
Assay data:323 Active, 134 Activity ≤ 1 µM, 9667 Tested
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
qHTS assay to identify small molecule agonists of the retinoic acid receptor (RAR) signaling pathway
Assay data:429 Active, 2 Activity ≤ 1 nM, 171 Activity ≤ 1 µM, 9315 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary
Assay data:1147 Active, 1 Activity ≤ 1 nM, 122 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary
Assay data:1063 Active, 1 Activity ≤ 1 nM, 58 Activity ≤ 1 µM, 10486 Tested
qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway
Assay data:523 Active, 1 Activity ≤ 1 nM, 117 Activity ≤ 1 µM, 9305 Tested
qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway
Assay data:98 Active, 5 Activity ≤ 1 µM, 2864 Tested
qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway
Assay data:152 Active, 15 Activity ≤ 1 µM, 2864 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:583 Active, 1 Activity ≤ 1 nM, 42 Activity ≤ 1 µM, 2810 Tested
qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5
Assay data:235 Active, 144 Activity ≤ 1 µM, 10486 Tested
Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)
Assay data:7 Active, 2 Activity ≤ 1 µM, 8 Tested
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