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Antiviral activity against Ebola virus trVLP assessed as reduction in RNA synthesis at 1 uM by qPCR analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against pseudovirus SARS-CoV spike protein infected in HeLa cells over expressing ACE2 assessed as inhibition on pseudovirus infection incubated for 52 hrs by luminescence based microplate reader analysis
Assay data:6 Active, 4 Activity ≤ 1 µM, 6 Tested
Inhibition of human recombinant Cathepsin L assessed as Kinact using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay
Assay data:6 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human cathepsin L
Assay data:7 Active, 6 Activity ≤ 1 µM, 10 Tested
Cathepsin L probe #2 dose-response testing
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
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