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Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: PE2_PLB cell viability assay
Assay data:851 Active, 15 Activity ≤ 1 nM, 274 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: UTMC2_PLB cell viability assay
Assay data:584 Active, 49 Activity ≤ 1 nM, 617 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: OPM1_PLB cell viability assay
Assay data:896 Active, 18 Activity ≤ 1 nM, 320 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: MM1R_ATCC cell viability assay
Assay data:822 Active, 12 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: MMM1_PLB cell viability assay
Assay data:911 Active, 7 Activity ≤ 1 nM, 657 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS26_JCRB cell viability assay
Assay data:699 Active, 23 Activity ≤ 1 nM, 366 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS20_JCRB cell viability assay
Assay data:588 Active, 31 Activity ≤ 1 nM, 546 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JIM1_ECACC cell viability assay
Assay data:457 Active, 27 Activity ≤ 1 nM, 619 Activity ≤ 1 µM, 1912 Tested
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as reduction in bacterial growth incubated for 72 hrs by two-fold dilution method
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of wild type Staphylococcus aureus gyrase assessed as compound concentration causing 50% induction of cleavage of covalently closed DNA substrate
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of wild type Staphylococcus aureus topoisomerase 4 assessed as compound concentration causing 50% induction of cleavage of covalently closed DNA substrate
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 measured after 24 hrs by ELISA
Assay data:9 Active, 3 Activity ≤ 1 µM, 11 Tested
Antibacterial activity against Escherichia coli CMCC 44568 measured after 24 hrs by ELISA
Assay data:9 Active, 3 Activity ≤ 1 µM, 41 Tested
Antibacterial activity against Escherichia coli CMCC 25922 measured after 24 hrs by ELISA
Assay data:5 Active, 3 Activity ≤ 1 µM, 41 Tested
Antibacterial activity against Staphylococcus aureus CMCC 25923 measured after 24 hrs by ELISA
Assay data:12 Active, 5 Activity ≤ 1 µM, 41 Tested
Antibacterial activity against Staphylococcus aureus CMCC(B) 26003 measured after 24 hrs by ELISA
Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC in CAMBH media using NBS plates, by OD(600)
Assay data:41 Active, 10 Activity ≤ 1 µM, 24161 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CAMBH media using NBS plates, by OD(600)
Assay data:58 Active, 16 Activity ≤ 1 µM, 4585 Tested
Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020); MIC in CAMBH media, using NBS plates, by OD(600)
Assay data:98 Active, 48 Activity ≤ 1 µM, 4588 Tested
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
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