BioAssay Links for PMC (Select 4025649) - PubChem BioAssay - NCBI

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Links from PMC

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Select item 13455801.

Human neurotrophic receptor tyrosine kinase 3 (Type VII RTKs: Neurotrophin receptor/Trk family)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: NT-3 growth factor receptor isoform d precursor

Assay data:4 Active, 4 Tested

AID:: 1345580

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13455472.

Human neurotrophic receptor tyrosine kinase 2 (Type VII RTKs: Neurotrophin receptor/Trk family)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: BDNF/NT-3 growth factors receptor isoform e precursor

Assay data:6 Active, 6 Tested

AID:: 1345547

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13455453.

Human neurotrophic receptor tyrosine kinase 1 (Type VII RTKs: Neurotrophin receptor/Trk family)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: high affinity nerve growth factor receptor isoform 1 precursor

Assay data:11 Active, 11 Tested

AID:: 1345545

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 6639454.

Inhibition of Tel-fused ROS in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase ROS

Assay data:6 Active, 6 Tested

AID:: 663945

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 6639385.

Cmax in Sprague-Dawley rat at 10 mg/kg, po

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 663938

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 6639376.

Cmax in Sprague-Dawley rat at 3 mg/kg, iv

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 663937

Summary Compounds, Active PubMed Citation

Select item 6639297.

Cmax in Balb/c mouse at 20 mg/kg, po

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 663929

Summary Compounds, Active PubMed Citation

Select item 6639288.

Cmax in Balb/c mouse at 5 mg/kg, iv

Source:: ChEMBL

Assay data:1 Tested

AID:: 663928

Summary PubMed Citation

Select item 6639239.

Inhibition of PDGFR in rat A10 cells

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 663923

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 66392210.

Inhibition of c-Kit in human Mo7e cells

Source:: ChEMBL

Protein Target:: Mast/stem cell growth factor receptor Kit

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 663922

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 66392111.

Antiproliferative activity against rat RIE cells expressing TRKA and NGF

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 663921

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 66391912.

Antiproliferative activity against mouse BA/F3 cells expressing TRKA and NGF

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 663919

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 66391813.

Inhibition of Tel-fused ZAP70 in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ZAP-70

Assay data:4 Active, 5 Tested

AID:: 663918

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66391714.

Inhibition of Tel-fused TIE1 in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:6 Active, 6 Tested

AID:: 663917

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66391615.

Inhibition of Tel-fused SRC in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Neuronal proto-oncogene tyrosine-protein kinase Src

Assay data:5 Active, 6 Tested

AID:: 663916

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66391516.

Inhibition of Tel-fused RON in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Macrophage-stimulating protein receptor

Assay data:4 Active, 6 Tested

AID:: 663915

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66391417.

Inhibition of Tel-fused RET in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase receptor Ret

Assay data:6 Active, 4 Activity ≤ 1 µM, 6 Tested

AID:: 663914

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 66385118.

Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Platelet-derived growth factor receptor beta

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 663851

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 66385019.

Inhibition of Tel-fused LYN in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lyn

Assay data:5 Active, 6 Tested

AID:: 663850

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66384920.

Inhibition of Tel-fused MET in mouse BA/F3 cells

Source:: ChEMBL

Protein Target:: Hepatocyte growth factor receptor

Assay data:4 Active, 5 Tested

AID:: 663849

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Activity (IC50, etc) ≤ 1 µM (17)
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (62)
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