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Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 at 0.5 to 1 times MIC90 incubated for 5 days in presence of thiourea
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 at 0.5 to 1 times MIC90 incubated for 5 days in presence of TEMPO
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 at 0.5 to 1 times MIC90 incubated for 5 days in presence of N-acetylcysteine
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 assessed as reduction in colony forming unit at 0.5 to 1 times MIC90 incubated for 5 days
Antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 carrying katG loss-of-function mutant assessed fold reduction in MIC at 1 to 2 times of MIC90 incubated for 5 days under solid agar medium
Assay data:2 Active, 2 Tested
Antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 carrying katG loss-of-function mutant assessed fold reduction in MIC at 1 to 2 times of MIC90 incubated for 5 days under liquid medium
Assay data:1 Active, 2 Tested
Antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 carrying katG loss-of-function mutant assessed fold reduction in MIC at 1 to 2 times of MIC90 incubated for 5 days
Assay data:2 Tested
SummaryPubMed Citation
Induction of oxidative stress Mycobacterium bovis BCG-pfurA-RFP ATCC 35734 assessed as activation of pfurA at 0.5 to 2 times MIC90 after 24 hrs by fluorescence assay
Induction of oxidative stress Mycobacterium bovis BCG-pfurA-RFP ATCC 35734 assessed as activation of pfurA after 24 hrs by fluorescence assay
Assay data:3 Tested
Induction of ROS generation in Mycobacterium bovis BCG ATCC 35734 at 2 times of MIC90 measured upto 24 hrs by cellrox-green reagent based assay
Induction of ROS generation in Mycobacterium bovis BCG ATCC 35734 at 2 times of MIC90 after 90 mins by cellrox-green reagent based assay
Induction of ROS generation in Mycobacterium bovis BCG ATCC 35734 at <= 1 times of MIC90 after 90 mins by cellrox-green reagent based assay
Induction of ROS generation in Mycobacterium bovis BCG ATCC 35734 after 90 mins by cellrox-green reagent based assay
Induction of cell envelope stress in Mycobacterium bovis BCG ATCC 35734 expressing piniBAC RFP at 100 times MIC90 after 24 hrs by fluorescence analysis
Induction of membrane permeabilization in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC after 8 hrs by SYTO9 and PI staining based fluorescence assay
Induction of cell membrane depolarization in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC after 8 hrs by DiOC2 dye based flourescence assay
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 assessed as fold reduction in viability at 40 times MIC90 preincubated for 20 days under oxygen deprived condition followed by compound addition and measured after 5 days
Ratio of MIC for antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 in absence of glycerol to MIC for antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 in presence of glycerol
Assay data:6 Tested
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 assessed as reduction in colony forming unit at 8 times MIC measured after 21 days by time-kill assay
Bactericidal activity against Mycobacterium bovis BCG ATCC 35734 assessed as fold reduction in viability at 4 times MIC measured over 14 days by time-kill assay
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