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Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 infected in human HaCaT cells assessed as reduction in amoeba-induced host cell cytopathogenicity at 100 ug/ml preincubated with amoeba for 2 hrs followed by incubation of suspension with host cell for 24 hrs by LDH release assay
Assay data:11 Active, 11 Tested
SummaryCompounds, ActivePubMed Citation
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 infected in human HaCaT cells assessed as reduction in amoeba-induced host cell cytopathogenicity at 100 ug/ml preincubated with amoeba for 2 hrs followed by incubation of suspension with host cell for 24 hrs by LDH release assay relative to control
Assay data:4 Tested
SummaryPubMed Citation
Inhibition of Acanthamoeba castellanii T4 genotype ATCC 50492 excystation at 100 ug/ml incubated with pre-formed cysts for 72 hrs by hemocytometric method
Assay data:16 Active, 16 Tested
Inhibition of Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites encystation at 100 ug/ml incubated for 72 hrs by hemocytometric method
Assay data:3 Active, 3 Tested
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 assessed as increase in pore formation at 100 ug/ml incubated for 2 hrs by FE-SEM analysis
Assay data:2 Active, 2 Tested
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 assessed as increase in surface disintegration at 100 ug/ml incubated for 2 hrs by FE-SEM analysis
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites assessed as reduction in viable cells at 100 ug/ml incubated for 24 hrs by trypan blue staining based hemocytometric method relative to control
Assay data:14 Tested
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites assessed as reduction in viable cells at 50 ug/ml incubated for 24 hrs by trypan blue staining based hemocytometric method relative to control
Assay data:15 Tested
Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites assessed as reduction in viable cells at 100 ug/ml incubated for 24 hrs by trypan blue staining based hemocytometric method
Assay data:1 Tested
Inhibition of dephosphorylated Acanthamoeba muscle myosin 1c by NADH-coupled spectrophotometric analysis
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of dephosphorylated Acanthamoeba non muscle myosin 2 by NADH-coupled spectrophotometric analysis
Antimicrobial activity against Acanthamoeba castellanii after 3 days by hemocytometer
Antimicrobial activity against Acanthamoeba castellanii
Assay data:1 Active, 1 Tested
Inhibition of tubulin in Acanthamoeba castellanii by alamar blue assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antimicrobial activity against Acanthamoeba castellanii assessed as number of viable cells/ml at 10 ug/ml upto 3 days by hemocytometer relative to control
Antimicrobial activity against Acanthamoeba castellanii assessed as decrease in viable cell concentration at 20 ug/ml after 3 days by hemocytometer
Antimicrobial activity against Acanthamoeba castellanii assessed as growth inhibition at 10 ug/ml after 3 days by hemocytometer relative to control
Antimicrobial activity against Acanthamoeba castellanii assessed as growth inhibition at 5 ug/ml after 3 days by hemocytometer
Antimicrobial activity against Acanthamoeba castellanii assessed as growth inhibition at 2 ug/ml after 3 days by hemocytometer
Antimicrobial activity against Acanthamoeba castellanii assessed as growth inhibition at 10 ug/ml upto 3 days by hemocytometer
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