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Antischistosomal activity against adult stage of Schistosoma japonicum assessed as inhibition of parasite motility at 100 nM measured after 48 hrs by microscopic method
Assay data:4 Active, 5 Tested
SummaryCompounds, ActivePubMed Citation
Antischistosomal activity against adult stage of Schistosoma japonicum assessed as parasite death at 100 nM measured after 72 hrs by microscopic method
Assay data:2 Active, 7 Tested
Antischistosomal activity against adult stage of Schistosoma japonicum assessed as inhibition of parasite motility at 100 nM measured after 24 to 72 hrs by microscopic method
Assay data:2 Active, 3 Tested
Antischistosomal activity against adult Schistosoma japonicum
Assay data:1 Active, 1 Tested
Antischistosomal activity against juvenile Schistosoma japonicum
Antischistosomal activity against adult Schistosoma japonicum assessed as worm death at 12.5 uM incubated for 120 hrs relative to control
Assay data:1 Tested
SummaryPubMed Citation
Antischistosomal activity against Schistosoma japonicum assessed as worm death at 10 uM incubated for 120 hrs relative to control
Assay data:6 Tested
Antischistosomal activity against adult Schistosoma japonicum infected in ICR mouse assessed as reduction in worm burden at 8 mg/kg, ip administered for 5 consecutive days
Antischistosomal activity against juvenile Schistosoma japonicum infected in ICR mouse assessed as reduction in worm burden at 8 mg/kg, ip administered for 5 consecutive days
Antischistosomal activity against larva Schistosoma japonicum infected in ICR mouse assessed as reduction in worm burden at 8 mg/kg, ip administered for 5 consecutive days
Antischistosomal activity against Schistosoma japonicum assessed as worm mortality at 5 ug/ml incubated for 72 hrs by microscopic method relative to control
Antischistosomal activity against Schistosoma japonicum assessed as worm mortality at 10 ug/ml incubated for 72 hrs by microscopic method relative to control
Assay data:2 Tested
Antischistosomal activity against Schistosoma japonicum at 10 uM incubated for 72 hrs by inverted microscopic method relative to control
Schistosomicidal-activity against adult Schistosoma japonicum at 10 uM incubated for 72 hrs by inverted microscopic method relative to control
Antischistosomal activity against Schistosoma japonicum infected in ICR mouse assessed as total worm reduction at 250 mg/kg, po administered as single dose relative to control
Antischistosomal activity against adult Schistosoma japonicum assessed as reduction in worm vitality at >10 uM incubated for 48 hrs relative to control
Antischistosomal activity against juvenile Schistosoma japonicum assessed as reduction in worm vitality at 25 uM incubated for 72 hrs relative to control
Concentration required to kill 50% of 42 day old worms 5 days after drug treatment.
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antischistosomal activity against Schistosoma japonicum
Antischistosomal activity against Schistosoma japonicum infected in mouse assessed as reduction in adult worm burden at 400 mg/kg, po administered as single dose relative to control
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