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Antibacterial activity against Vibrio parahaemolyticus assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method
Assay data:7 Active, 3 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Induction of bacterial resistance in Vibrio parahaemolyticus ATCC17802 assessed as fold increase in MIC treated over 30 serial passages measured after 24 hrs
Assay data:3 Tested
SummaryPubMed Citation
Induction of bacterial resistance in Vibrio parahaemolyticus ATCC17802 assessed as change in MIC treated over 30 serial passages measured after 24 hrs
Assay data:1 Tested
Induction of outer membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as increase fluorescence intensity measured upto 15 mins by NPN uptake assay
Induction of outer membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as increase fluorescence intensity at 0.5 to 2 times of MIC by NPN uptake assay
Binding affinity to Vibrio parahaemolyticus ATCC17802 cell membrane assessed as increase in fluorescence intensity measured after 120 mins by flow cytometry analysis (Rvb = 1.88%)
Binding affinity to Vibrio parahaemolyticus ATCC17802 cell membrane assessed as increase in fluorescence intensity measured after 30 mins by flow cytometry analysis (Rvb = 1.85%)
Induction of cytoplasmic membrane permeabilization in Vibrio parahaemolyticus ATCC1780 assessed as calcein transmembrane diffusion into interior of gaint unilamellar vesicles by measuring time to equilibrium between inside and outside of vesicles at 2 ug/mL by confocal microscopy based calcein-AM leakage assay
Induction of bacterial inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as calcein leakage from large unilamellar vesicles liposomes at 5 times MIC by fluorescence based microplate reader assay
Induction of bacterial inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as calcein leakage from large unilamellar vesicles liposomes at 5 times MIC measured upto 60 mins by fluorescence based microplate reader assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as increase in PI fluorescence intensity at 5 times MIC by propidium iodide penetration assay
Assay data:10 Active, 10 Tested
Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as calcein leakage at 5 times MIC by calcein-AM leakage assay
Assay data:4 Tested
Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 at 5 times MIC measured upto 200 mins by propidium iodide penetration assay
Assay data:5 Active, 5 Tested
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as massive cell collapse incubated at 5 times MIC and measured after 15 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as surface fibrosis incubated at 5 times MIC and measured after 15 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as cellular inclusion leakage incubated at 5 times MIC and measured after 15 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as cellular inclusion leakage incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as surface fibrosis incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as massive cell collapse incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis
Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as cellular inclusion leakage incubated at 5 times MIC and measured after 180 mins by scanning electron microscopy based analysis
Assay data:3 Active, 3 Tested
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