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Items: 20

1.
LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development
Lining Zhou, Yu Tian, Fang Guo, Bin Yu, Jiali Li, Huaxi Xu, Zhaoliang Su
Cancer Immunol Immunother. 2020 May; 69(5): 835–846. Published online 2020 Feb 15. doi: 10.1007/s00262-020-02511-0
PMCID:
PMC11027865
ArticlePDF–6.2M
2.
Functional elements of the cis-regulatory lincRNA-p21
Lauren Winkler, Maria Jimenez, Joshua T. Zimmer, Adam Williams, Matthew D. Simon, Nadya Dimitrova
Cell Rep. Author manuscript; available in PMC 2022 May 19.
Published in final edited form as: Cell Rep. 2022 Apr 19; 39(3): 110687. doi: 10.1016/j.celrep.2022.110687
PMCID:
PMC9118141
ArticlePDF–1.4M
3.
TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in mice
Xiaolong Tu, Yuanyuan Zhang, Xiuxiu Zheng, Jia Deng, Huanan Li, Zhiqian Kang, Zhipeng Cao, Zhen Huang, Zhi Ding, Lei Dong, Jiangning Chen, Yuhui Zang, Junfeng Zhang
Sci Rep. 2017; 7: 2957. Published online 2017 Jun 7. doi: 10.1038/s41598-017-03175-0
PMCID:
PMC5462818
ArticlePDF–17M
4.
In vivo characterization of Linc-p21 reveals functional cis-regulatory DNA elements
Abigail F Groff, Diana B Sanchez-Gomez, Marcela ML Soruco, Chiara Gerhardinger, A. Rasim Barutcu, Eric Li, Lara Elcavage, Olivia Plana, Lluvia V Sanchez, James C Lee, Martin Sauvageau, John L Rinn
Cell Rep. Author manuscript; available in PMC 2016 Sep 8.
Published in final edited form as: Cell Rep. 2016 Aug 23; 16(8): 2178–2186. Published online 2016 Aug 11. doi: 10.1016/j.celrep.2016.07.050
PMCID:
PMC5014909
ArticlePDF–1.7M
5.
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Mitchell Guttman, Ido Amit, Manuel Garber, Courtney French, Michael F. Lin, David Feldser, Maite Huarte, Or Zuk, Bryce W. Carey, John P. Cassady, Moran N. Cabili, Rudolf Jaenisch, Tarjei S. Mikkelsen, Tyler Jacks, Nir Hacohen, Bradley E. Bernstein, Manolis Kellis, Aviv Regev, John L. Rinn, Eric S. Lander
Nature. Author manuscript; available in PMC 2009 Sep 30.
Published in final edited form as: Nature. 2009 Mar 12; 458(7235): 223–227. Published online 2009 Feb 1. doi: 10.1038/nature07672
PMCID:
PMC2754849
ArticlePDF–1.9M
6.
LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning
Shan-Shan Meng, Xiu-Ping Xu, Wei Chang, Zhong-Hua Lu, Li-Li Huang, Jing-Yuan Xu, Ling Liu, Hai-Bo Qiu, Yi Yang, Feng-Mei Guo
Stem Cell Res Ther. 2018; 9: 280. Published online 2018 Oct 25. doi: 10.1186/s13287-018-1031-x
PMCID:
PMC6202870
ArticlePDF–6.2M
7.
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Xichen Bao, Haitao Wu, Xihua Zhu, Xiangpeng Guo, Andrew P Hutchins, Zhiwei Luo, Hong Song, Yongqiang Chen, Keyu Lai, Menghui Yin, Lingxiao Xu, Liang Zhou, Jiekai Chen, Dongye Wang, Baoming Qin, Jon Frampton, Hung-Fat Tse, Duanqing Pei, Huating Wang, Biliang Zhang, Miguel A Esteban
Cell Res. 2015 Jan; 25(1): 80–92. Published online 2014 Dec 16. doi: 10.1038/cr.2014.165
PMCID:
PMC4650593
ArticlePDF–1.1M
8.
LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint
Nadya Dimitrova, Jesse R. Zamudio, Robyn M. Jong, Dylan Soukup, Rebecca Resnick, Kavitha Sarma, Amanda J. Ward, Arjun Raj, Jeannie Lee, Phillip A. Sharp, Tyler Jacks
Mol Cell. Author manuscript; available in PMC 2015 Jun 5.
Published in final edited form as: Mol Cell. 2014 Jun 5; 54(5): 777–790. Published online 2014 May 22. doi: 10.1016/j.molcel.2014.04.025
PMCID:
PMC4103188
ArticlePDF–2.6M
9.
LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis and Atherosclerosis by Enhancing p53 Activity
Gengze Wu, Jin Cai, Yu Han, Jinghai Chen, Zhan-Peng Huang, Caiyu Chen, Yue Cai, Hefei Huang, Yujia Yang, Yukai Liu, Zaicheng Xu, Duofen He, Xiaoqun Zhang, Xiaoyun Hu, Luca Pinello, Dan Zhong, Fengtian He, Guo-Cheng Yuan, Da-Zhi Wang, Chunyu Zeng
Circulation. Author manuscript; available in PMC 2015 Oct 21.
Published in final edited form as: Circulation. 2014 Oct 21; 130(17): 1452–1465. Published online 2014 Aug 25. doi: 10.1161/CIRCULATIONAHA.114.011675
Correction in:
Circulation. 2019 Apr 23; 139(17): e887.
PMCID:
PMC4244705
ArticlePDF–1.3M
10.
A large intergenic non-coding RNA induced by p53 mediates global gene repression in the p53 response
Maite Huarte, Mitchell Guttman, David Feldser, Manuel Garber, Magdalena J. Koziol, Daniela Kenzelmann-Broz, Ahmad M. Khalil, Or Zuk, Ido Amit, Michal Rabani, Laura D. Attardi, Aviv Regev, Eric S. Lander, Tyler Jacks, John L. Rinn
Cell. Author manuscript; available in PMC 2011 Aug 6.
Published in final edited form as: Cell. 2010 Aug 6; 142(3): 409–419. doi: 10.1016/j.cell.2010.06.040
PMCID:
PMC2956184
ArticlePDF–1.5M
11.
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
Loyal A. Goff, Abigail F. Groff, Martin Sauvageau, Zachary Trayes-Gibson, Diana B. Sanchez-Gomez, Michael Morse, Ryan D. Martin, Lara E. Elcavage, Stephen C. Liapis, Meryem Gonzalez-Celeiro, Olivia Plana, Eric Li, Chiara Gerhardinger, Giulio S. Tomassy, Paola Arlotta, John L. Rinn
Proc Natl Acad Sci U S A. 2015 Jun 2; 112(22): 6855–6862. Published online 2015 Jun 1. doi: 10.1073/pnas.1411263112
PMCID:
PMC4460505
ArticlePDF–2.4M
12.
Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs
Ka-Man Venus Lai, Guochun Gong, Amanda Atanasio, José Rojas, Joseph Quispe, Julita Posca, Derek White, Mei Huang, Daria Fedorova, Craig Grant, Lawrence Miloscio, Gustavo Droguett, William T. Poueymirou, Wojtek Auerbach, George D. Yancopoulos, David Frendewey, John Rinn, David M. Valenzuela
PLoS One. 2015; 10(4): e0125522. Published online 2015 Apr 24. doi: 10.1371/journal.pone.0125522
PMCID:
PMC4409293
ArticlePDF–20M
13.
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ota, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
Sci Rep. 2017; 7: 40692. Published online 2017 Jan 20. doi: 10.1038/srep40692
PMCID:
PMC5247747
ArticlePDF–1.9M
14.
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
Martin Sauvageau, Loyal A Goff, Simona Lodato, Boyan Bonev, Abigail F Groff, Chiara Gerhardinger, Diana B Sanchez-Gomez, Ezgi Hacisuleyman, Eric Li, Matthew Spence, Stephen C Liapis, William Mallard, Michael Morse, Mavis R Swerdel, Michael F D’Ecclessis, Jennifer C Moore, Venus Lai, Guochun Gong, George D Yancopoulos, David Frendewey, Manolis Kellis, Ronald P Hart, David M Valenzuela, Paola Arlotta, John L Rinn
eLife. 2013; 2: e01749. Published online 2013 Dec 31. doi: 10.7554/eLife.01749
PMCID:
PMC3874104
ArticlePDF–4.6M
15.
lncRNAdb: a reference database for long noncoding RNAs
Paulo P. Amaral, Michael B. Clark, Dennis K. Gascoigne, Marcel E. Dinger, John S. Mattick
Nucleic Acids Res. 2011 Jan; 39(Database issue): D146–D151. Published online 2010 Nov 25. doi: 10.1093/nar/gkq1138
PMCID:
PMC3013714
ArticlePDF–3.0M
16.
The Vertebrate Genome Annotation browser 10 years on
Jennifer L. Harrow, Charles A. Steward, Adam Frankish, James G. Gilbert, Jose M. Gonzalez, Jane E. Loveland, Jonathan Mudge, Dan Sheppard, Mark Thomas, Stephen Trevanion, Laurens G. Wilming
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D771–D779. Published online 2013 Dec 6. doi: 10.1093/nar/gkt1241
PMCID:
PMC3964964
ArticlePDF–11M
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
ArticlePDF–493K
18.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
ArticlePDF–481K
19.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
ArticlePDF–3.4M
20.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
ArticlePDF–1.4M

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