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Items: 1 to 20 of 42

1.
Inhibition and transport mechanisms of the ABC transporter hMRP5
Ying Huang, Chenyang Xue, Ruiqian Bu, Cang Wu, Jiachen Li, Jinqiu Zhang, Jinyu Chen, Zhaoying Shi, Yonglong Chen, Yong Wang, Zhongmin Liu
Nat Commun. 2024; 15: 4811. Published online 2024 Jun 6. doi: 10.1038/s41467-024-49204-1
PMCID:
PMC11156954
AbstractArticlePDF–5.4M
2.
ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma
Wenbin Huang, Kunling Chen, Yishi Lu, Donghui Zhang, Yuan Cheng, Liuran Li, Weimei Huang, Guolin He, Hangyu Liao, Lei Cai, Yujun Tang, Liang Zhao, Mingxin Pan
Neoplasia. 2021 Dec; 23(12): 1227–1239. Published online 2021 Nov 9. doi: 10.1016/j.neo.2021.11.002
PMCID:
PMC8591347
AbstractArticlePDF–5.7M
3.
Pan-cancer analysis and single-cell analysis revealed the role of ABCC5 transporter in hepatocellular carcinoma
Liang Chen, Zhonghua Yang, Yuan Cao, Yiming Hu, Wei Bao, Dan Wu, Li Hu, Jiaheng Xie, Hongzhu Yu
Channels (Austin) 2021; 15(1): 541–554. Published online 2021 Sep 8. doi: 10.1080/19336950.2021.1968592
PMCID:
PMC8437464
AbstractArticlePDF–3.5M
4.
ABCC5 Transporter is a Novel Type 2 Diabetes Susceptibility Gene in European and African American Populations
Kenan Direk, Winston Lau, Kerrin S Small, Nikolas Maniatis, Toby Andrew
Ann Hum Genet. 2014 Sep; 78(5): 333–344. Published online 2014 Aug 12. doi: 10.1111/ahg.12072
PMCID:
PMC4173130
AbstractArticlePDF–425K
5.
ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone
Anna A Mourskaia, Eitan Amir, Zhifeng Dong, Kerstin Tiedemann, Sean Cory, Atilla Omeroglu, Nicholas Bertos, Véronique Ouellet, Mark Clemons, George L Scheffer, Morag Park, Michael Hallett, Svetlana V Komarova, Peter M Siegel
Breast Cancer Res. 2012; 14(6): R149. Published online 2012 Nov 22. doi: 10.1186/bcr3361
PMCID:
PMC4053136
AbstractArticlePDF–3.8M
6.
Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
Jelena Stojic, Heidi Stöhr, Bernhard HF Weber
BMC Mol Biol. 2007; 8: 42. Published online 2007 May 23. doi: 10.1186/1471-2199-8-42
PMCID:
PMC1890297
AbstractArticlePDF–530K
7.
Expression and Localization of the Multidrug Resistance Protein 5 (MRP5/ABCC5), a Cellular Export Pump for Cyclic Nucleotides, in Human Heart
Peter Dazert, Konrad Meissner, Silke Vogelgesang, Björn Heydrich, Lothar Eckel, Michael Böhm, Rolf Warzok, Reinhold Kerb, Ulrich Brinkmann, Elke Schaeffeler, Matthias Schwab, Ingolf Cascorbi, Gabriele Jedlitschky, Heyo K. Kroemer
Am J Pathol. 2003 Oct; 163(4): 1567–1577. doi: 10.1016/S0002-9440(10)63513-4
PMCID:
PMC1868287
AbstractArticlePDF–767K
8.
Expression, Localization, and Function of MRP5 (ABCC5), a Transporter for Cyclic Nucleotides, in Human Placenta and Cultured Human Trophoblasts : Effects of Gestational Age and Cellular Differentiation
Henriette E.U. Meyer zu Schwabedissen, Markus Grube, Björn Heydrich, Knud Linnemann, Christoph Fusch, Heyo K. Kroemer, Gabriele Jedlitschky
Am J Pathol. 2005 Jan; 166(1): 39–48. doi: 10.1016/S0002-9440(10)62230-4
PMCID:
PMC1602292
AbstractArticlePDF–1.9M
9.
FOXM1 Promotes Drug Resistance in Cervical Cancer Cells by Regulating ABCC5 Gene Transcription
Youxiang Hou, Zhanfei Dong, Wei Zhong, Linglong Yin, Xiong Li, Gulina Kuerban, He Huang
Biomed Res Int. 2022; 2022: 3032590. Published online 2022 Jan 31. doi: 10.1155/2022/3032590
PMCID:
PMC8820921
AbstractArticlePDF–1.9M
10.
The FOXM1–ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells
Youxiang Hou, Qianling Zhu, Zheng Li, Yongbo Peng, Xiaohui Yu, Bowen Yuan, Yijun Liu, Youhong Liu, Linglong Yin, Yuchong Peng, Zhenghua Jiang, Jinping Li, Bowen Xie, Yumei Duan, Guolin Tan, Kurban Gulina, Zhicheng Gong, Lunquan Sun, Xuegong Fan, Xiong Li
Cell Death Dis. 2017 Mar; 8(3): e2659. Published online 2017 Mar 9. doi: 10.1038/cddis.2017.53
PMCID:
PMC5386553
AbstractArticlePDF–3.3M
11.
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs
Robert S. Jansen, Sunny Mahakena, Marcel de Haas, Piet Borst, Koen van de Wetering
J Biol Chem. 2015 Dec 18; 290(51): 30429–30440. Published online 2015 Oct 29. doi: 10.1074/jbc.M115.692103
PMCID:
PMC4683265
AbstractArticlePDF–3.6M
12.
N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids
Robert S. Jansen, Ruben Addie, Remco Merkx, Alexander Fish, Sunny Mahakena, Onno B. Bleijerveld, Maarten Altelaar, Lodewijk IJlst, Ronald J. Wanders, P. Borst, Koen van de Wetering
Proc Natl Acad Sci U S A. 2015 May 26; 112(21): 6601–6606. Published online 2015 May 11. doi: 10.1073/pnas.1424638112
PMCID:
PMC4450436
AbstractArticlePDF–839K
13.
Molecular markers in circulating tumour cells from metastatic colorectal cancer patients
Paola Gazzaniga, Angela Gradilone, Arianna Petracca, Chiara Nicolazzo, Cristina Raimondi, Roberto Iacovelli, Giuseppe Naso, Enrico Cortesi
J Cell Mol Med. 2010 Aug; 14(8): 2073–2077. Published online 2010 Jul 1. doi: 10.1111/j.1582-4934.2010.01117.x
PMCID:
PMC3822998
AbstractArticlePDF–509K
14.
Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance
Marek Kucka, Karla Kretschmannova, Takayo Murano, Chung-Pu Wu, Hana Zemkova, Suresh V. Ambudkar, Stanko S. Stojilkovic
Mol Pharmacol. 2010 Feb; 77(2): 270–279. doi: 10.1124/mol.109.059386
PMCID:
PMC2812068
AbstractArticlePDF–2.8M
15.
Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)
Aina W Ravna, Ingebrigt Sylte, Georg Sager
Theor Biol Med Model. 2007; 4: 33. Published online 2007 Sep 6. doi: 10.1186/1742-4682-4-33
PMCID:
PMC2211457
AbstractArticlePDF–1.7M
16.
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
Jan Wijnholds, Carla A. A. M. Mol, Liesbeth van Deemter, Marcel de Haas, George L. Scheffer, Frank Baas, Jos H. Beijnen, Rik J. Scheper, Sigrid Hatse, Erik De Clercq, Jan Balzarini, Piet Borst
Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13): 7476–7481. Published online 2000 Jun 6. doi: 10.1073/pnas.120159197
PMCID:
PMC16570
AbstractArticlePDF–204K
17.
Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy
Nikolai V. Litviakov, Nadezhda V. Cherdyntseva, Matvey M. Tsyganov, Elena M. Slonimskaya, Marina K. Ibragimova, Polina V. Kazantseva, Julia Kzhyshkowska, Eugeniy L. Choinzonov
Oncotarget. 2016 Feb 16; 7(7): 7829–7841. Published online 2016 Jan 20. doi: 10.18632/oncotarget.6953
PMCID:
PMC4884957
AbstractArticlePDF–1.9M
18.
Modulatory effects of plant polyphenols on human multidrug resistance proteins 1, 4, and 5 (ABCC1, 4, and 5)
Chung-Pu Wu, Anna Maria Calcagno, Stephen B. Hladky, Suresh V. Ambudkar, Margery A. Barrand
FEBS J. Author manuscript; available in PMC 2006 Sep 1.
Published in final edited form as: FEBS J. 2005 Sep; 272(18): 4725–4740. doi: 10.1111/j.1742-4658.2005.04888.x
PMCID:
PMC1350838
AbstractArticlePDF–915K
19.
ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma
Monisha E. Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K. Cornes, Li-Jia Chen, Chunyan Qiao, K. Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Do Tan, Khaled Abu-Amero, Shamira A. Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A. Tajudin, Ching-Lin Ho, Clement C. Y. Tham, Ileana Soto, Paul T. K. Chew, Hon-Tym Wong, Balekudaru Shantha, Masako Kuroda, Essam A. Osman, Guangxian Tang, Sujie Fan, Hailin Meng, Hua Wang, Bo Feng, Victor H. K. Yong, Serena M. L. Ting, Yang Li, Ya-Xing Wang, Zheng Li, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Daniel H. Su, Seng-Chee Loon, R. Rand Allingham, Michael A. Hauser, Nagaswamy Soumittra, Vedam L. Ramprasad, Naushin Waseem, Azhany Yaakub, Kee-Seng Chia, Govindasamy Kumaramanickavel, Tina T. Wong, Alicia C. How, Tran Nguyen Bich Chau, Cameron P. Simmons, Jin-Xin Bei, Yi-Xin Zeng, Shomi S. Bhattacharya, Mingzhi Zhang, Donald T. Tan, Yik-Ying Teo, Saleh A. Al-Obeidan, Do Nhu Hon, E-Shyong Tai, Seang-Mei Saw, Paul J. Foster, Lingam Vijaya, Jost B. Jonas, Tien-Yin Wong, Simon W. M. John, Chi-Pui Pang, Eranga N. Vithana, Ningli Wang, Tin Aung
PLoS Genet. 2014 Mar; 10(3): e1004089. Published online 2014 Mar 6. doi: 10.1371/journal.pgen.1004089
Correction in:
PLoS Genet. 2014 Apr; 10(4): e1004352.
PMCID:
PMC3945113
AbstractArticlePDF–281K
20.
Efflux Protein Expression in Human Stem Cell-Derived Retinal Pigment Epithelial Cells
Kati Juuti-Uusitalo, Hanna Vaajasaari, Tuomas Ryhänen, Susanna Narkilahti, Riitta Suuronen, Eliisa Mannermaa, Kai Kaarniranta, Heli Skottman
PLoS One. 2012; 7(1): e30089. Published online 2012 Jan 17. doi: 10.1371/journal.pone.0030089
PMCID:
PMC3260202
AbstractArticlePDF–1.4M

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