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Select item 48509331.

The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1

Sanguine Byun, Seung Ho Shin, Eunjung Lee, Jihoon Lee, Sung-Young Lee, Lee Farrand, Sung Keun Jung, Yong-Yeon Cho, Soo-Jong Um, Hong-Sig Sin, Youn-Ja Kwon, Chengjuan Zhang, Benjamin K. Tsang, Ann M. Bode, Hyong Joo Lee, Ki Won Lee, Zigang Dong

Carcinogenesis. 2015 Dec; 36(12): 1580–1589. Published online 2015 Oct 13. doi: 10.1093/carcin/bgv148

PMCID:: PMC4850933

Abstract Article PDF–4.9M

Select item 84309982.

Androgen Receptor-Mediated Nuclear Transport of NRDP1 in Prostate Cancer Cells Is Associated with Worse Patient Outcomes

Thomas Steele, Anhao Sam, Shawna Evans, Elizabeth Browning, Sheryl Krig, Katelyn Macias, Adarsh Konda, Salma Siddiqui, Blythe Durbin-Johnson, Paramita Ghosh, Ruth Vinall

Cancers (Basel) 2021 Sep; 13(17): 4425. Published online 2021 Sep 2. doi: 10.3390/cancers13174425

PMCID:: PMC8430998

Abstract Article PDF–2.9M

Select item 47594703.

Nrdp1S, short variant of Nrdp1, inhibits human glioma progression by increasing Nrdp1‐mediated ErbB3 ubiquitination and degradation

Yuxuan Wu, Lei Wang, Hanmo Bao, Shenshan Zou, Chunling Fu, Hui Gong, Yong Gao, Yuan Tang, Rutong Yu, Hengliang Shi

J Cell Mol Med. 2016 Mar; 20(3): 422–429. Published online 2015 Nov 27. doi: 10.1111/jcmm.12735

PMCID:: PMC4759470

Abstract Article PDF–703K

Select item 39616804.

Oligomerization of the Nrdp1 E3 Ubiquitin Ligase Is Necessary for Efficient Autoubiquitination but Not ErbB3 Ubiquitination

Ignat Printsev, Lily Yen, Colleen Sweeney, Kermit L. Carraway, III

J Biol Chem. 2014 Mar 21; 289(12): 8570–8578. Published online 2014 Feb 11. doi: 10.1074/jbc.M113.527036

PMCID:: PMC3961680

Abstract Article PDF–1.4M

Select item 38893975.

Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity

Katherine T. Lewandowski, Helen Piwnica-Worms

J Cell Sci. 2014 Jan 15; 127(2): 315–327. doi: 10.1242/jcs.129148

PMCID:: PMC3889397

Abstract Article

Select item 31333966.

Quantity Control of the ErbB3 Receptor Tyrosine Kinase at the Endoplasmic Reticulum

William H. D. Fry, Catalina Simion, Colleen Sweeney, Kermit L. Carraway, III

Mol Cell Biol. 2011 Jul; 31(14): 3009–3018. doi: 10.1128/MCB.05105-11

PMCID:: PMC3133396

Abstract Article PDF–3.3M

Select item 31157357.

RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

Joris Wauman, Leentje De Ceuninck, Nele Vanderroost, Sam Lievens, Jan Tavernier

J Cell Sci. 2011 Mar 15; 124(6): 921–932. doi: 10.1242/jcs.078055

PMCID:: PMC3115735

Abstract Article

Select item 29054758.

Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells

Liqun Chen, Salma Siddiqui, Swagata Bose, Benjamin Mooso, Alfredo Asuncion, Roble G. Bedolla, Ruth Vinall, Clifford G. Tepper, Regina Gandour-Edwards, XuBao Shi, Xiao-Hua Lu, Javed Siddiqui, Arul M. Chinnaiyan, Rohit Mehra, Ralph W. deVere White, Kermit L. Carraway, III, Paramita M. Ghosh

Cancer Res. Author manuscript; available in PMC 2011 Jul 15.

Published in final edited form as: Cancer Res. 2010 Jul 15; 70(14): 5994–6003. Published online 2010 Jun 29. doi: 10.1158/0008-5472.CAN-09-4440

PMCID:: PMC2905475

Abstract Article PDF–2.7M

Select item 22033319.

Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3

Samuel Bouyain, Daniel J. Leahy

Protein Sci. 2007 Apr; 16(4): 654–661. doi: 10.1110/ps.062700307

PMCID:: PMC2203331

Abstract Article PDF–635K

Select item 970905910.

m⁶A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation

Wei Zeng, Jin-Feng Zhu, Jian Guo, Gen-Jie Huang, Li-Sha Ai, Yu Zeng, Wang-Jun Liao

Cell Death Dis. 2022 Nov; 13(11): 1008. Published online 2022 Nov 29. doi: 10.1038/s41419-022-05451-y

PMCID:: PMC9709059

Abstract Article PDF–8.2M

Select item 620401011.

Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer

Satu Luhtala, Synnöve Staff, Anne Kallioniemi, Minna Tanner, Jorma Isola

BMC Cancer. 2018; 18: 1045. Published online 2018 Oct 26. doi: 10.1186/s12885-018-4917-1

PMCID:: PMC6204010

Abstract Article PDF–1.7M

Select item 557292312.

Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1

Narmadha Reddy Gangula, Subbareddy Maddika

J Biol Chem. 2017 Aug 25; 292(34): 13947–13958. Published online 2017 Jul 10. doi: 10.1074/jbc.M117.782896

PMCID:: PMC5572923

Abstract Article PDF–2.8M

Select item 13750613.

Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

Xiao-Bo Qiu, Alfred L. Goldberg

Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23): 14843–14848. Published online 2002 Oct 31. doi: 10.1073/pnas.232580999

Correction in:: Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 17219.

PMCID:: PMC137506

Abstract Article PDF–330K

Select item 12243914.

An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

A. John Diamonti, Pamela M. Guy, Caryn Ivanof, Karen Wong, Colleen Sweeney, Kermit L. Carraway, III

Proc Natl Acad Sci U S A. 2002 Mar 5; 99(5): 2866–2871. Published online 2002 Feb 26. doi: 10.1073/pnas.052709799

PMCID:: PMC122439

Abstract Article PDF–331K

Select item 578006015.

Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy

Gemma Pearson, Biaoxin Chai, Tracy Vozheiko, Xueying Liu, Malathi Kandarpa, Robert C. Piper, Scott A. Soleimanpour

Diabetes. 2018 Feb; 67(2): 265–277. Published online 2017 Nov 27. doi: 10.2337/db17-0321

PMCID:: PMC5780060

Abstract Article PDF–2.2M

Select item 293789616.

Post-transcriptional Mechanisms Contribute to the Suppression of the ErbB3 Negative Regulator Protein Nrdp1 in Mammary Tumors

Ellen Q. Ingalla, Jamie K. Miller, Jessica H. Wald, Heather C. Workman, Rouminder P. Kaur, Lily Yen, William H. D. Fry, Alexander D. Borowsky, Lawrence J. T. Young, Colleen Sweeney, Kermit L. Carraway, III

J Biol Chem. 2010 Sep 10; 285(37): 28691–28697. Published online 2010 Jul 13. doi: 10.1074/jbc.M110.127977

PMCID:: PMC2937896

Abstract Article PDF–1.5M

Select item 182049617.

Neuregulin-Induced ErbB3 Downregulation Is Mediated by a Protein Stability Cascade Involving the E3 Ubiquitin Ligase Nrdp1

Zhongwei Cao, Xiuli Wu, Lily Yen, Colleen Sweeney, Kermit L. Carraway, III

Mol Cell Biol. 2007 Mar; 27(6): 2180–2188. Published online 2007 Jan 8. doi: 10.1128/MCB.01245-06

PMCID:: PMC1820496

Abstract Article PDF–745K

Select item 771035618.

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

Kirsteen M Tullett, Peck Szee Tan, Hae-Young Park, Ralf B Schittenhelm, Nicole Michael, Rong Li, Antonia N Policheni, Emily Gruber, Cheng Huang, Alex J Fulcher, Jillian C Danne, Peter E Czabotar, Linda M Wakim, Justine D Mintern, Georg Ramm, Kristen J Radford, Irina Caminschi, Meredith O'Keeffe, Jose A Villadangos, Mark D Wright, Marnie E Blewitt, William R Heath, Ken Shortman, Anthony W Purcell, Nicos A Nicola, Jian-Guo Zhang, Mireille H Lahoud

eLife. 2020; 9: e63452. Published online 2020 Dec 2. doi: 10.7554/eLife.63452

PMCID:: PMC7710356

Abstract Article PDF–2.6M

Select item 543994419.

RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes

Delphine Masschaele, Leentje De Ceuninck, Joris Wauman, Dieter Defever, Frank Stenner, Sam Lievens, Frank Peelman, Jan Tavernier

PLoS One. 2017; 12(5): e0178132. Published online 2017 May 22. doi: 10.1371/journal.pone.0178132

PMCID:: PMC5439944

Abstract Article PDF–5.6M

Select item 685704220.

CACYBP Enhances Cytoplasmic Retention of P27^Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation

Yi-Fan Lian, Yan-Lin Huang, Yao-Jun Zhang, Dong-Mei Chen, Jia-Liang Wang, Huan Wei, Yan-Hua Bi, Zhi-Wu Jiang, Peng Li, Min-Shan Chen, Yue-Hua Huang

Theranostics. 2019; 9(26): 8392–8408. Published online 2019 Oct 22. doi: 10.7150/thno.36838

PMCID:: PMC6857042

Abstract Article PDF–2.6M

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