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Items: 1 to 20 of 75

1.
Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity
Dhruva Katrekar, Yichen Xiang, Nathan Palmer, Anushka Saha, Dario Meluzzi, Prashant Mali
eLife. 2022; 11: e75555. Published online 2022 Jan 19. doi: 10.7554/eLife.75555
PMCID:
PMC8809894
AbstractArticlePDF–3.0M
2.
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
Sonia Jimeno, Rosario Prados-Carvajal, María Jesús Fernández-Ávila, Sonia Silva, Domenico Alessandro Silvestris, Martín Endara-Coll, Guillermo Rodríguez-Real, Judit Domingo-Prim, Fernando Mejías-Navarro, Amador Romero-Franco, Silvia Jimeno-González, Sonia Barroso, Valeriana Cesarini, Andrés Aguilera, Angela Gallo, Neus Visa, Pablo Huertas
Nat Commun. 2021; 12: 5512. Published online 2021 Sep 17. doi: 10.1038/s41467-021-25790-2
PMCID:
PMC8448848
AbstractArticlePDF–1.7M
3.
Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing
Guo Li, Yihan Wang, Xiangyang Li, Yuzhe Wang, Xingxu Huang, Jianen Gao, Xiaoxiang Hu
Cell Commun Signal. 2021; 19: 84. Published online 2021 Aug 11. doi: 10.1186/s12964-021-00716-z
PMCID:
PMC8356384
AbstractArticlePDF–1.1M
4.
Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy
Reza Maroofian, Jiří Sedmík, Neda Mazaheri, Marcello Scala, Maha S Zaki, Liam P Keegan, Reza Azizimalamiri, Mahmoud Issa, Gholamreza Shariati, Alireza Sedaghat, Christian Beetz, Peter Bauer, Hamid Galehdari, Mary A O’Connell, Henry Houlden
J Med Genet. 2021 Jul; 58(7): 495–504. Published online 2020 Jul 27. doi: 10.1136/jmedgenet-2020-107048
PMCID:
PMC8327408
AbstractArticlePDF–1.8M
5.
Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition
Alexander S Thuy-Boun, Justin M Thomas, Herra L Grajo, Cody M Palumbo, SeHee Park, Luan T Nguyen, Andrew J Fisher, Peter A Beal
Nucleic Acids Res. 2020 Aug 20; 48(14): 7958–7972. Published online 2020 Jun 29. doi: 10.1093/nar/gkaa532
PMCID:
PMC7641318
AbstractArticlePDF–3.2M
6.
ADAR2 Is Involved in Self and Nonself Recognition of Borna Disease Virus Genomic RNA in the Nucleus
Mako Yanai, Shohei Kojima, Madoka Sakai, Ryo Komorizono, Keizo Tomonaga, Akiko Makino
J Virol. 2020 Mar; 94(6): e01513-19. Prepublished online 2019 Dec 18. Published online 2020 Feb 28. doi: 10.1128/JVI.01513-19
PMCID:
PMC7158724
AbstractArticlePDF–2.1M
7.
Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures
Tiong Yang Tan, Jiří Sedmík, Mark P. Fitzgerald, Rivka Sukenik Halevy, Liam P. Keegan, Ingo Helbig, Lina Basel-Salmon, Lior Cohen, Rachel Straussberg, Wendy K. Chung, Mayada Helal, Reza Maroofian, Henry Houlden, Jane Juusola, Simon Sadedin, Lynn Pais, Katherine B. Howell, Susan M. White, John Christodoulou, Mary A. O’Connell
Am J Hum Genet. 2020 Apr 2; 106(4): 467–483. Published online 2020 Mar 26. doi: 10.1016/j.ajhg.2020.02.015
PMCID:
PMC7118584
AbstractArticlePDF–3.3M
8.
Function of low ADARB1 expression in lung adenocarcinoma
Xiang Wang, Zhijie Xu, Xinxin Ren, Xi Chen, Jie Wei, Wei Lin, Zhi Li, Chunlin Ou, Zhicheng Gong, Yuanliang Yan
PLoS One. 2019; 14(9): e0222298. Published online 2019 Sep 6. doi: 10.1371/journal.pone.0222298
PMCID:
PMC6730894
AbstractArticlePDF–2.8M
9.
How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs
Justin M. Thomas, Peter A. Beal
Bioessays. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Bioessays. 2017 Apr; 39(4): 10.1002/bies.201600187. Published online 2017 Feb 20. doi: 10.1002/bies.201600187
PMCID:
PMC5501306
AbstractArticlePDF–1021K
10.
A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme
Deepanjan Paul, Ashis Narayan Sinha, Arjun Ray, Megha Lal, Subhashree Nayak, Anchal Sharma, Bharati Mehani, Debasish Mukherjee, Saurabh V. Laddha, Ashish Suri, Chitra Sarkar, Arijit Mukhopadhyay
Sci Rep. 2017; 7: 2466. Published online 2017 May 26. doi: 10.1038/s41598-017-02397-6
PMCID:
PMC5446428
AbstractArticlePDF–2.3M
11.
Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method
Yuru Wang, Peter A. Beal
Nucleic Acids Res. 2016 Nov 16; 44(20): 9872–9880. Published online 2016 Sep 9. doi: 10.1093/nar/gkw799
PMCID:
PMC5175354
AbstractArticlePDF–3.0M
12.
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity
Melissa M. Matthews, Justin M. Thomas, Yuxuan Zheng, Kiet Tran, Kelly J. Phelps, Anna I. Scott, Jocelyn Havel, Andrew J. Fisher, Peter A. Beal
Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Oct 11.
Published in final edited form as: Nat Struct Mol Biol. 2016 May; 23(5): 426–433. Published online 2016 Apr 11. doi: 10.1038/nsmb.3203
PMCID:
PMC4918759
AbstractArticlePDF–2.6M
13.
Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2
Kelly J. Phelps, Kiet Tran, Tristan Eifler, Anna I. Erickson, Andrew J. Fisher, Peter A. Beal
Nucleic Acids Res. 2015 Jan 30; 43(2): 1123–1132. Published online 2015 Jan 6. doi: 10.1093/nar/gku1345
PMCID:
PMC4333395
AbstractArticlePDF–781K
14.
Abnormal expression of an ADAR2 alternative splicing variant in gliomas downregulates adenosine-to-inosine RNA editing
Jun Wei, Zhaohui Li, Chao Du, Bin Qi, Xingli Zhao, Liping Wang, Lirong Bi, Guan Wang, Xuan Zhang, Xiaoyun Su, Yuzhuo Pan, Yu Tian
Acta Neurochir (Wien) 2014; 156(6): 1135–1142. Published online 2014 Feb 11. doi: 10.1007/s00701-014-2004-1
PMCID:
PMC4030101
AbstractArticlePDF–4.5M
15.
ADAR2-Mediated Editing of miR-214 and miR-122 Precursor and Antisense RNA Transcripts in Liver Cancers
Wan-Hsin Liu, Chao-Hung Chen, Kun-Huei Yeh, Chiao-Ling Li, Yi-Jinn Wu, Ding-Shinn Chen, Pei-Jer Chen, Shiou-Hwei Yeh
PLoS One. 2013; 8(12): e81922. Published online 2013 Dec 27. doi: 10.1371/journal.pone.0081922
PMCID:
PMC3873926
AbstractArticlePDF–3.2M
16.
ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis
F Galeano, C Rossetti, S Tomaselli, L Cifaldi, M Lezzerini, M Pezzullo, R Boldrini, L Massimi, C M Di Rocco, F Locatelli, A Gallo
Oncogene. 2013 Feb 21; 32(8): 998–1009. Published online 2012 Apr 23. doi: 10.1038/onc.2012.125
PMCID:
PMC3579159
AbstractArticlePDF–3.8M
17.
A novel tissue-specific alternatively spliced form of the A-to-I RNA editing enzyme ADAR2
Lily Agranat, Joseph Sperling, Ruth Sperling
RNA Biol. Author manuscript; available in PMC 2011 Mar 22.
Published in final edited form as: RNA Biol. 2010 Mar; 7(2): 253–262. Published online 2010 Mar 17. doi: 10.4161/rna.7.2.11568
PMCID:
PMC3062093
AbstractArticlePDF–3.0M
18.
Changes in Serum Adenosine Deaminase Activity during Normal Pregnancy
Soo Jin Lee, Han Sung Hwang, Bit Na Rae Kim, Min A Kim, Jae Wook Lee, Yong Won Park, Young Han Kim
J Korean Med Sci. 2007 Aug; 22(4): 718–721. Published online 2007 Aug 31. doi: 10.3346/jkms.2007.22.4.718
PMCID:
PMC2693826
AbstractArticlePDF–79K
19.
Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing
Mark R. Macbeth, Heidi L. Schubert, Andrew P. VanDemark, Arunth T. Lingam, Christopher P. Hill, Brenda L. Bass
Science. Author manuscript; available in PMC 2007 Apr 10.
Published in final edited form as: Science. 2005 Sep 2; 309(5740): 1534–1539. doi: 10.1126/science.1113150
PMCID:
PMC1850959
AbstractArticlePDF–1.5M
20.
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding
MARK R. MACBETH, ARUNTH T. LINGAM, BRENDA L. BASS
RNA. 2004 Oct; 10(10): 1563–1571. doi: 10.1261/rna.7920904
PMCID:
PMC1370643
AbstractArticlePDF–259K

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