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Items: 1 to 20 of 70

1.
Ligand and Target Discovery by Fragment-Based Screening in Human Cells
Christopher G. Parker, Andrea Galmozzi, Yujia J. Wang, Bruno E. Correia, Kenji Sasaki, Christopher M. Joslyn, Arthur S. Kim, Cullen L. Cavallaro, Michael Lawrence, Stephen R. Johnson, Iñigo Narvaiza, Enrique Saez, Benjamin F. Cravatt
Cell. Author manuscript; available in PMC 2017 Oct 8.
Published in final edited form as: Cell. 2017 Jan 26; 168(3): 527–541.e29. Published online 2017 Jan 19. doi: 10.1016/j.cell.2016.12.029
PMCID:
PMC5632530
AbstractArticlePDF–1.9M
2.
PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function
Andrea Galmozzi, Bernard P. Kok, Arthur S. Kim, J. Rafael Montenegro-Burke, Jae Y. Lee, Roberto Spreafico, Sarah Mosure, Verena Albert, Rigo Cintron-Colon, Cristina Godio, William R. Webb, Bruno Conti, Laura A. Solt, Douglas Kojetin, Christopher G. Parker, John J. Peluso, James K. Pru, Gary Siuzdak, Benjamin F. Cravatt, Enrique Saez
Nature. Author manuscript; available in PMC 2020 May 20.
Published in final edited form as: Nature. 2019 Dec; 576(7785): 138–142. Published online 2019 Nov 20. doi: 10.1038/s41586-019-1774-2
PMCID:
PMC6895438
AbstractArticlePDF–5.8M
3.
Identification of a novel putative interaction partner of the nucleoporin ALADIN
Ramona Jühlen, Dana Landgraf, Angela Huebner, Katrin Koehler
Biol Open. 2016 Nov 15; 5(11): 1697–1705. Published online 2016 Oct 17. doi: 10.1242/bio.021162
PMCID:
PMC5155539
AbstractArticlePDF–6.0M
4.
A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase
Robert B. Piel, III, Mesafint T. Shiferaw, Ajay A. Vashisht, Jason Marcero, Jeremy Praissman, John D. Phillips, James A. Wohlschlegel, Amy E. Medlock
Biochemistry. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Biochemistry. 2016 Sep 20; 55(37): 5204–5217. Published online 2016 Sep 9. doi: 10.1021/acs.biochem.6b00756
PMCID:
PMC5278647
AbstractArticlePDF–1.2M
5.
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter
Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra
Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1
PMCID:
PMC8629785
AbstractArticlePDF–10M
6.
A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy
Dong He, Tao Xin, Bo Pang, Jun Sun, Zi Hao Liu, Zhen Qin, Xiao Shuai Ji, Fan Yang, Yan Bang Wei, Zi Xiao Wang, Jia Jia Gao, Qi Pang, Qian Liu
J Exp Clin Cancer Res. 2022; 41: 349. Published online 2022 Dec 17. doi: 10.1186/s13046-022-02543-7
PMCID:
PMC9758949
AbstractArticlePDF–18M
7.
Integrated proteomics-based physical and functional mapping of AXL kinase signaling pathways and inhibitors define its role in cell migration
Anurima Majumder, Sina Hosseinian, Mia Stroud, Emma Adhikari, James J. Saller, Matthew A. Smith, Guolin Zhang, Shruti Agarwal, Marc Creixell, Benjamin S. Meyer, Fumi Kinose, Kiah Bowers, Bin Fang, Paul A. Stewart, Eric A. Welsh, Theresa A. Boyle, Aaron S. Meyer, John M. Koomen, Eric B. Haura
Mol Cancer Res. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Mol Cancer Res. 2022 Apr 1; 20(4): 542–555. doi: 10.1158/1541-7786.MCR-21-0275
PMCID:
PMC8983558
AbstractArticlePDF–2.4M
8.
Claudin-4 localization in epithelial ovarian cancer
Margaret C. Neville, Patricia G. Webb, Heidi K. Baumgartner, Benjamin G. Bitler
Heliyon. 2022 Oct; 8(10): e10862. Published online 2022 Oct 4. doi: 10.1016/j.heliyon.2022.e10862
PMCID:
PMC9552118
AbstractArticlePDF–4.5M
9.
Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2
Norbert Volkmar, Christian M Gawden‐Bone, James C Williamson, Jonathon Nixon‐Abell, James A West, Peter H St George‐Hyslop, Arthur Kaser, Paul J Lehner
EMBO J. 2022 Oct; 41(19): e110777. Published online 2022 Aug 22. doi: 10.15252/embj.2022110777
PMCID:
PMC9531299
AbstractArticlePDF–6.9M
10.
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006
PMCID:
PMC9753471
AbstractArticlePDF–4.3M
11.
Probing nuclear pore complex architecture with proximity-dependent biotinylation
Dae In Kim, Birendra KC, Wenhong Zhu, Khatereh Motamedchaboki, Valérie Doye, Kyle J. Roux
Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24): E2453–E2461. Published online 2014 Jun 3. doi: 10.1073/pnas.1406459111
PMCID:
PMC4066523
AbstractArticlePDF–1.6M
12.
Maternal and Fetal Genetic Associations of PTGER3 and PON1 with Preterm Birth
Kelli K. Ryckman, Nils-Halvdan Morken, Marquitta J. White, Digna R. Velez, Ramkumar Menon, Stephen J. Fortunato, Per Magnus, Scott M. Williams, Bo Jacobsson
PLoS One. 2010; 5(2): e9040. Published online 2010 Feb 3. doi: 10.1371/journal.pone.0009040
PMCID:
PMC2815792
AbstractArticlePDF–899K
13.
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome
Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A. Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsak
Front Mol Neurosci. 2019; 12: 224. Published online 2019 Sep 20. doi: 10.3389/fnmol.2019.00224
PMCID:
PMC6763791
AbstractArticlePDF–3.6M
14.
Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy
Jin-Mi Heo, Nathan J. Harper, Joao A. Paulo, Mamie Li, Qikai Xu, Margaret Coughlin, Stephen J. Elledge, J. Wade Harper
Sci Adv. 2019 Nov; 5(11): eaay4624. Published online 2019 Nov 6. doi: 10.1126/sciadv.aay4624
PMCID:
PMC6834391
AbstractArticlePDF–2.6M
15.
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
Kyle J. Roux, Dae In Kim, Manfred Raida, Brian Burke
J Cell Biol. 2012 Mar 19; 196(6): 801–810. doi: 10.1083/jcb.201112098
PMCID:
PMC3308701
AbstractArticlePDF–1.6M
16.
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants
Digna R. Velez, Stephen Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon
Am J Obstet Gynecol. Author manuscript; available in PMC 2016 Apr 12.
Published in final edited form as: Am J Obstet Gynecol. 2009 Feb; 200(2): 209.e1–209.27. Published online 2008 Nov 18. doi: 10.1016/j.ajog.2008.08.051
PMCID:
PMC4829203
AbstractArticlePDF–164K
17.
Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants
Ramkumar Menon, Brad Pearce, Digna R Velez, Mario Merialdi, Scott M Williams, Stephen J Fortunato, Poul Thorsen
Reprod Biol Endocrinol. 2009; 7: 62. Published online 2009 Jun 15. doi: 10.1186/1477-7827-7-62
PMCID:
PMC2714850
AbstractArticlePDF–8.4M
18.
Preterm Birth in Caucasians Is Associated with Coagulation and Inflammation Pathway Gene Variants
Digna R. Velez, Stephen J. Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon
PLoS One. 2008; 3(9): e3283. Published online 2008 Sep 26. doi: 10.1371/journal.pone.0003283
PMCID:
PMC2553267
AbstractArticlePDF–185K
19.
HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis
Carlos A. Barrero, Prasun K. Datta, Satarupa Sen, Satish Deshmane, Shohreh Amini, Kamel Khalili, Salim Merali
PLoS One. 2013; 8(7): e68376. Published online 2013 Jul 12. doi: 10.1371/journal.pone.0068376
PMCID:
PMC3709966
AbstractArticlePDF–1.3M
20.
MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer
Xiaofan Zhang, Hushan Yang, J.Jack Lee, Edward Kim, Scott M. Lippman, Fadlo R. Khuri, Margaret R. Spitz, Reuben Lotan, Waun K. Hong, Xifeng Wu
Carcinogenesis. 2010 Dec; 31(12): 2118–2123. Published online 2010 Sep 5. doi: 10.1093/carcin/bgq177
PMCID:
PMC3105587
AbstractArticlePDF–236K

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