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Select item 112200181.

Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression

Hao Peng, Meng Yang, Kun Feng, Qingpeng Lv, Yewei Zhang

Signal Transduct Target Ther. 2024; 9: 169. Published online 2024 Jul 3. doi: 10.1038/s41392-024-01887-0

PMCID:: PMC11220018

Abstract Article PDF–9.2M

Select item 106926502.

Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells

Parvin Yenki, Satyam Bhasin, Liang Liu, Noushin Nabavi, Chi Wing Cheng, Kevin J Tam, James W Peacock, Hans H Adomat, Tabitha Tombe, Ladan Fazli, Larissa Ivanova, Christopher Dusek, Shahram Khosravi, Emma S Tomlinson Guns, Yuzhuo Wang, Ralph Buttyan, Martin E Gleave, Christopher J Ong

Endocr Relat Cancer. 2023 Dec 1; 30(12): e230010. Prepublished online 2023 Oct 6. Published online 2023 Nov 6. doi: 10.1530/ERC-23-0010

PMCID:: PMC10692650

Abstract Article PDF–2.4M

Select item 90555713.

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)₂D₃ in osteoblasts

Jussi Ryynänen, Carsten Kriebitzsch, Mark B. Meyer, Iris Janssens, J. Wesley Pike, Lieve Verlinden, Annemieke Verstuyf

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Oct; 173: 185–193. Published online 2017 Feb 9. doi: 10.1016/j.jsbmb.2017.02.005

PMCID:: PMC9055571

Abstract Article PDF–1.9M

Select item 82635474.

Whole-genome sequencing identifies functional noncoding variation in SEMA3C that cosegregates with dyslexia in a multigenerational family

Amaia Carrion-Castillo, Sara B. Estruch, Ben Maassen, Barbara Franke, Clyde Francks, Simon E. Fisher

Hum Genet. 2021; 140(8): 1183–1200. Published online 2021 Jun 2. doi: 10.1007/s00439-021-02289-w

PMCID:: PMC8263547

Abstract Article PDF–1.2M

Select item 78767675.

Effect of semaphorin 3C gene variants in multifactorial Hirschsprung disease

Gunadi, Fiko Ryantono, Raman Sethi, Marcellus, Alvin Santoso Kalim, Priscillia Imelda, Devy Melati, Susan Simanjaya, William Widitjiarso, Ririd Tri Pitaka, Nur Arfian, Kristy Iskandar, Akhmad Makhmudi, Poh San Lai

J Int Med Res. 2021 Feb; 49(2): 0300060520987789. Published online 2021 Feb 8. doi: 10.1177/0300060520987789

PMCID:: PMC7876767

Abstract Article PDF–805K

Select item 76592866.

Semaphorin 3C is involved in the progression of gastric cancer

Hideyo Miyato, Nelson Hirokazu Tsuno, Joji Kitayama

Cancer Sci. 2012 Nov; 103(11): 1961–1966. Published online 2012 Oct 15. doi: 10.1111/cas.12003

PMCID:: PMC7659286

Abstract Article PDF–1.7M

Select item 73051097.

Semaphorin 3 C is a Novel Adipokine Representing Exercise-Induced Improvements of Metabolism in Metabolically Healthy Obese Young Males

Ji Sun Nam, Chul Woo Ahn, Hye Jun Park, Yu Sik Kim

Sci Rep. 2020; 10: 10005. Published online 2020 Jun 19. doi: 10.1038/s41598-020-67004-7

PMCID:: PMC7305109

Abstract Article PDF–1.5M

Select item 68886308.

The Anti-Tumorigenic Activity of Sema3C in the Chick Embryo Chorioallantoic Membrane Model

Indrė Valiulytė, Rūta Curkūnavičiūtė, Laura Ribokaitė, Arunas Kazlauskas, Monika Vaitkevičiūtė, Kęstutis Skauminas, Angelija Valančiūtė

Int J Mol Sci. 2019 Nov; 20(22): 5672. Published online 2019 Nov 12. doi: 10.3390/ijms20225672

PMCID:: PMC6888630

Abstract Article PDF–2.7M

Select item 55975779.

Semaphorin 3 C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells

Kevin J. Tam, Daniel H. F. Hui, Wilson W. Lee, Mingshu Dong, Tabitha Tombe, Ivy Z. F. Jiao, Shahram Khosravi, Ario Takeuchi, James W. Peacock, Larissa Ivanova, Igor Moskalev, Martin E. Gleave, Ralph Buttyan, Michael E. Cox, Christopher J. Ong

Sci Rep. 2017; 7: 11501. Published online 2017 Sep 13. doi: 10.1038/s41598-017-11914-6

PMCID:: PMC5597577

Abstract Article PDF–1.9M

Select item 520125110.

A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization

Shira Toledano, Huayi Lu, Agustina Palacio, Keren Ziv, Ofra Kessler, Shlomit Schaal, Gera Neufeld, Yoreh Barak

PLoS One. 2016; 11(12): e0168122. Published online 2016 Dec 30. doi: 10.1371/journal.pone.0168122

PMCID:: PMC5201251

Abstract Article PDF–1.4M

Select item 516003811.

Class 3 semaphorins in cardiovascular development

Donatella Valdembri, Donatella Regano, Federica Maione, Enrico Giraudo, Guido Serini

Cell Adh Migr. 2016; 10(6): 641–651. Published online 2016 Jul 20. doi: 10.1080/19336918.2016.1212805

PMCID:: PMC5160038

Abstract Article PDF–540K

Select item 510999812.

Class 3 semaphorins induce F-actin reorganization in human dendritic cells: Role in cell migration

Sabrina Curreli, Bin Sheng Wong, Olga Latinovic, Konstantinos Konstantopoulos, Nicholas M. Stamatos

J Leukoc Biol. 2016 Dec; 100(6): 1323–1334. Published online 2016 Jul 12. doi: 10.1189/jlb.2A1114-534R

PMCID:: PMC5109998

Abstract Article

Select item 445082713.

High level of Sema3C is associated with glioma malignancy

Paulina Vaitkienė, Daina Skiriutė, Giedrius Steponaitis, Kęstutis Skauminas, Arimantas Tamašauskas, Arunas Kazlauskas

Diagn Pathol. 2015; 10: 58. Published online 2015 Jun 2. doi: 10.1186/s13000-015-0298-9

PMCID:: PMC4450827

Abstract Article PDF–604K

Select item 418163114.

The emerging role of class-3 semaphorins and their neuropilin receptors in oncology

Patrick Nasarre, Robert M Gemmill, Harry A Drabkin

Onco Targets Ther. 2014; 7: 1663–1687. Published online 2014 Sep 24. doi: 10.2147/OTT.S37744

PMCID:: PMC4181631

Abstract Article PDF–744K

Select item 339714915.

Semaphorins in kidney development and disease: modulators of ureteric bud branching, vascular morphogenesis, and podocyte-endothelial crosstalk

Kimberly Reidy, Alda Tufro

Pediatr Nephrol. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: Pediatr Nephrol. 2011 Sep; 26(9): 1407–1412. Published online 2011 Feb 20. doi: 10.1007/s00467-011-1769-1

PMCID:: PMC3397149

Abstract Article PDF–762K

Select item 2510116.

Identification of semaphorin E as a non-MDR drug resistance gene of human cancers

Tesshi Yamada, Ritsuko Endo, Masahiro Gotoh, Setsuo Hirohashi

Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26): 14713–14718. doi: 10.1073/pnas.94.26.14713

PMCID:: PMC25101

Abstract Article PDF–467K

Select item 1096378917.

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer

Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong

Sci Rep. 2024; 14: 7082. Published online 2024 Mar 25. doi: 10.1038/s41598-024-57854-w

PMCID:: PMC10963789

Abstract Article PDF–4.5M

Select item 1011916618.

Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastoma

Jing Hao, Xiangzi Han, Haidong Huang, Xingjiang Yu, Jiankang Fang, Jianjun Zhao, Richard A. Prayson, Shideng Bao, Jennifer S. Yu

Nat Commun. 2023; 14: 2262. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37397-w

Correction in:: Nat Commun. 2023; 14: 6018.

PMCID:: PMC10119166

Abstract Article PDF–3.1M

Select item 426806619.

Sema3C Promotes The Survival and Tumorigenicity of Glioma Stem Cells Through Rac1 Activation

Jianghong Man, Jocelyn Shoemake, Wenchao Zhou, Xiaoguang Fang, Qiulian Wu, Anthony Rizzo, Richard Prayson, Shideng Bao, Jeremy N. Rich, Jennifer S. Yu

Cell Rep. Author manuscript; available in PMC 2014 Dec 16.

Published in final edited form as: Cell Rep. 2014 Dec 11; 9(5): 1812–1826. Published online 2014 Nov 20. doi: 10.1016/j.celrep.2014.10.055