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Items: 1 to 20 of 24

1.
Ostα−/− mice are not protected from western diet‐induced weight gain
Christine L. Hammond, Sadie G. Wheeler, Nazzareno Ballatori, Patricia M. Hinkle
Physiol Rep. 2015 Jan; 3(1): e12263. Published online 2015 Jan 27. doi: 10.14814/phy2.12263
PMCID:
PMC4387766
AbstractArticlePDF–416K
2.
Ostα−/− mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity
Sadie G. Wheeler, Christine L. Hammond, François R. Jornayvaz, Varman T. Samuel, Gerald I. Shulman, Carol J. Soroka, James L. Boyer, Patricia M. Hinkle, Nazzareno Ballatori
Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1; 306(5): G425–G438. Published online 2013 Dec 31. doi: 10.1152/ajpgi.00368.2013
PMCID:
PMC3949021
AbstractArticle
3.
Molecular Mechanisms of Altered Bile Acid Homeostasis in Organic Solute Transporter-Alpha Knockout Mice
Tian Lan, Jamie Haywood, Anuradha Rao, Paul A. Dawson
Dig Dis. 2011 Jun; 29(1): 18–22. doi: 10.1159/000324124
PMCID:
PMC3202926
AbstractArticlePDF–155K
4.
Ostα depletion protects liver from oral bile acid load
Carol J. Soroka, Heino Velazquez, Albert Mennone, Nazzareno Ballatori, James L. Boyer
Am J Physiol Gastrointest Liver Physiol. 2011 Sep; 301(3): G574–G579. Published online 2011 Jun 30. doi: 10.1152/ajpgi.00141.2011
PMCID:
PMC3174539
AbstractArticle
5.
Mouse organic solute transporter α deficiency enhances renal excretion of bile acids and attenuates cholestasis
Carol J. Soroka, Albert Mennone, Lee R. Hagey, Nazzareno Ballatori, James L. Boyer
Hepatology. Author manuscript; available in PMC 2011 Jan 1.
Published in final edited form as: Hepatology. 2010 Jan; 51(1): 181–190. doi: 10.1002/hep.23265
PMCID:
PMC2819820
AbstractArticlePDF–642K
6.
Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice
Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson
JCI Insight. 2023 Mar 22; 8(6): e149360. Published online 2023 Mar 22. doi: 10.1172/jci.insight.149360
PMCID:
PMC10070106
AbstractArticlePDF–3.1M
7.
Neurosteroid transport by the organic solute transporter OSTα-OSTβ
Fang Fang, Whitney V. Christian, Sadie G. Gorman, Mei Cui, Jiaoti Huang, Kim Tieu, Nazzareno Ballatori
J Neurochem. Author manuscript; available in PMC 2011 Oct 1.
Published in final edited form as: J Neurochem. 2010 Oct; 115(1): 220–233. Published online 2010 Aug 12. doi: 10.1111/j.1471-4159.2010.06920.x
PMCID:
PMC2939961
AbstractArticlePDF–2.3M
8.
Ostα-Ostβ is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver
Nazzareno Ballatori, Fang Fang, Whitney V. Christian, Na Li, Christine L. Hammond
Am J Physiol Gastrointest Liver Physiol. 2008 Jul; 295(1): G179–G186. Published online 2008 May 22. doi: 10.1152/ajpgi.90319.2008
PMCID:
PMC2494730
AbstractArticle
9.
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions
Alex Zaufel, Sandra M.W. van de Wiel, Lu Yin, Günter Fauler, Daphne Chien, Xinzhong Dong, John F. Gilmer, Jennifer K. Truong, Paul A. Dawson, Stan F. J. van de Graaf, Peter Fickert, Tarek Moustafa
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1; 1867(8): 166153. Published online 2021 Apr 22. doi: 10.1016/j.bbadis.2021.166153
PMCID:
PMC8177068
AbstractArticlePDF–1.5M
10.
Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Tian Lan, Anuradha Rao, Jamie Haywood, Nancy D. Kock, Paul A. Dawson
J Hepatol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Hepatol. 2012 Aug; 57(2): 359–365. Published online 2012 Apr 25. doi: 10.1016/j.jhep.2012.03.025
PMCID:
PMC3575595
AbstractArticlePDF–1.7M
11.
Heterodimerization, trafficking and membrane topology of the two proteins, Ostα and Ostβ, that constitute the organic solute and steroid transporter
Na Li, Zhifeng Cui, Fang Fang, Jin Young Lee, Nazzareno Ballatori
Biochem J. 2007 Nov 1; 407(Pt 3): 363–372. Prepublished online 2007 Jul 24. Published online 2007 Oct 12. doi: 10.1042/BJ20070716
PMCID:
PMC2275063
AbstractArticlePDF–737K
12.
The organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis
Anuradha Rao, Jamie Haywood, Ann L. Craddock, Martin G. Belinsky, Gary D. Kruh, Paul A. Dawson
Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3891–3896. Published online 2008 Feb 21. doi: 10.1073/pnas.0712328105
PMCID:
PMC2268840
AbstractArticlePDF–1.1M
13.
The Heteromeric Organic Solute Transporter α-β, Ostα-Ostβ, Is an Ileal Basolateral Bile Acid Transporter
Paul A. Dawson, Melissa Hubbert, Jamie Haywood, Ann L. Craddock, Noa Zerangue, Whitney V. Christian, Nazzareno Ballatori
J Biol Chem. Author manuscript; available in PMC 2005 Sep 21.
Published in final edited form as: J Biol Chem. 2005 Feb 25; 280(8): 6960–6968. Published online 2004 Nov 24. doi: 10.1074/jbc.M412752200
PMCID:
PMC1224727
AbstractArticlePDF–1.9M
14.
Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice
Tian Lan, Jamie Haywood, Paul A. Dawson
Atherosclerosis. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Atherosclerosis. 2013 Aug; 229(2): 374–380. Published online 2013 May 28. doi: 10.1016/j.atherosclerosis.2013.05.017
PMCID:
PMC3724224
AbstractArticlePDF–1.4M
15.
β-Subunit of the Ostα-Ostβ Organic Solute Transporter Is Required Not Only for Heterodimerization and Trafficking but Also for Function
Whitney V. Christian, Na Li, Patricia M. Hinkle, Nazzareno Ballatori
J Biol Chem. 2012 Jun 15; 287(25): 21233–21243. Published online 2012 Apr 25. doi: 10.1074/jbc.M112.352245
PMCID:
PMC3375545
AbstractArticlePDF–2.9M
16.
Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels
Laurent Vergnes, Jessica M. Lee, Robert G. Chin, Johan Auwerx, Karen Reue
Cell Metab. Author manuscript; available in PMC 2014 Jun 4.
Published in final edited form as: Cell Metab. 2013 Jun 4; 17(6): 916–928. doi: 10.1016/j.cmet.2013.04.007
PMCID:
PMC3956443
AbstractArticlePDF–3.9M
17.
Maternal bile acid transporter deficiency promotes neonatal demise
Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz
Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186
PMCID:
PMC4598356
AbstractArticlePDF–1.5M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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