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Select item 51336981.

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

Alireza Noormohammadi, Amirabbas Khodakarami, Ricardo Gutierrez-Garcia, Hyun Ju Lee, Seda Koyuncu, Tim König, Christina Schindler, Isabel Saez, Azra Fatima, Christoph Dieterich, David Vilchez

Nat Commun. 2016; 7: 13649. Published online 2016 Nov 28. doi: 10.1038/ncomms13649

PMCID:: PMC5133698

Abstract Article PDF–1.6M

Select item 42460892.

The Molecular Chaperone TRiC/CCT Binds to the Trp-Asp 40 (WD40) Repeat Protein WDR68 and Promotes Its Folding, Protein Kinase DYRK1A Binding, and Nuclear Accumulation

Yoshihiko Miyata, Takeshi Shibata, Masato Aoshima, Takuichi Tsubata, Eisuke Nishida

J Biol Chem. 2014 Nov 28; 289(48): 33320–33332. Published online 2014 Oct 22. doi: 10.1074/jbc.M114.586115

PMCID:: PMC4246089

Abstract Article PDF–2.6M

Select item 66295823.

The chaperonin TRiC/CCT associates with Prefoldin through a conserved electrostatic interface essential for cellular proteostasis

Daniel Gestaut, Soung Hun Roh, Boxue Ma, Grigore Pintilie, Lukasz A. Joachimiak, Alexander Leitner, Thomas Walzthoeni, Ruedi Aebersold, Wah Chiu, Judith Frydman

Cell. Author manuscript; available in PMC 2020 Apr 18.

Published in final edited form as: Cell. 2019 Apr 18; 177(3): 751–765.e15. Published online 2019 Apr 4. doi: 10.1016/j.cell.2019.03.012

PMCID:: PMC6629582

Abstract Article PDF–4.1M

Select item 35816234.

Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitro

Kelly M. Knee, Oksana A. Sergeeva, Jonathan A. King

Cell Stress Chaperones. 2013 Mar; 18(2): 137–144. Published online 2012 Aug 13. doi: 10.1007/s12192-012-0357-z

PMCID:: PMC3581623

Abstract Article PDF–377K

Select item 28918565.

Human Cytomegalovirus UL29/28 Protein Interacts with Components of the NuRD Complex Which Promote Accumulation of Immediate-Early RNA

Scott S. Terhune, Nathaniel J. Moorman, Ileana M. Cristea, John Paul Savaryn, Christian Cuevas-Bennett, Michael P. Rout, Brian T. Chait, Thomas Shenk

PLoS Pathog. 2010 Jun; 6(6): e1000965. Published online 2010 Jun 24. doi: 10.1371/journal.ppat.1000965

PMCID:: PMC2891856

Abstract Article PDF–2.2M

Select item 76609116.

The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation

Franck Chesnel, Anne Couturier, Adrien Alusse, Jean-Philippe Gagné, Guy G. Poirier, Dominique Jean, François-Michel Boisvert, Pauline Hascoet, Luc Paillard, Yannick Arlot-Bonnemains, Xavier Le Goff

PLoS Genet. 2020 Nov; 16(11): e1009183. Published online 2020 Nov 2. doi: 10.1371/journal.pgen.1009183

PMCID:: PMC7660911

Abstract Article PDF–3.5M

Select item 49313447.

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

Mark R. Woodford, Diana M. Dunn, Adam R. Blanden, Dante Capriotti, David Loiselle, Chrisostomos Prodromou, Barry Panaretou, Philip F. Hughes, Aaron Smith, Wendi Ackerman, Timothy A. Haystead, Stewart N. Loh, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour

Nat Commun. 2016; 7: 12037. Published online 2016 Jun 29. doi: 10.1038/ncomms12037

PMCID:: PMC4931344

Abstract Article PDF–5.6M

Select item 48468928.

DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFκb negative regulator PPM1B

Haiyu Wang, Yusheng Chen, Jun Han, Qingyang Meng, Qiulei Xi, Guohao Wu, Bo Zhang

Am J Transl Res. 2016; 8(2): 405–418. Published online 2016 Feb 15.

PMCID:: PMC4846892

Abstract Article PDF–3.2M

Select item 96840309.

ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma

Roberto Ferrarese, Annalisa Izzo, Geoffroy Andrieux, Simon Lagies, Johanna Paulina Bartmuss, Anie Priscilla Masilamani, Alix Wasilenko, Daniela Osti, Stefania Faletti, Rana Schulzki, Shuai Yuan, Eva Kling, Valentino Ribecco, Dieter Henrik Heiland, Stefan Tholen, Marco Prinz, Giuliana Pelicci, Bernd Kammerer, Melanie Boerries, Maria Stella Carro

Life Sci Alliance. 2023 Jan; 6(1): e202201400. Published online 2022 Nov 22. doi: 10.26508/lsa.202201400

PMCID:: PMC9684030

Abstract Article PDF–3.3M

Select item 343392510.

Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking

Dale S. Haines, J. Eugene Lee, Stephen L. Beauparlant, Dane B. Kyle, Willem den Besten, Michael J. Sweredoski, Robert L. J. Graham, Sonja Hess, Raymond J. Deshaies

Mol Cell Proteomics. 2012 Jun; 11(6): M111.016444. Published online 2012 Feb 14. doi: 10.1074/mcp.M111.016444

PMCID:: PMC3433925

Abstract Article PDF–939K

Select item 584754111.

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Alex Pines, Madelon Dijk, Matthew Makowski, Elisabeth M. Meulenbroek, Mischa G. Vrouwe, Yana van der Weegen, Marijke Baltissen, Pim J. French, Martin E. van Royen, Martijn S. Luijsterburg, Leon H. Mullenders, Michiel Vermeulen, Wim Vermeulen, Navraj S. Pannu, Haico van Attikum

Nat Commun. 2018; 9: 1040. Published online 2018 Mar 12. doi: 10.1038/s41467-018-03484-6

PMCID:: PMC5847541

Abstract Article PDF–4.7M

Select item 476081912.

Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation

Allison Craney, Aileen Kelly, Luying Jia, Indro Fedrigo, Hongtao Yu, Michael Rape

Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): 1540–1545. Published online 2016 Jan 25. doi: 10.1073/pnas.1522423113

PMCID:: PMC4760819

Abstract Article PDF–1.1M

Select item 432914313.

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

Adam Freund, Franklin L. Zhong, Andrew S. Venteicher, Zhaojing Meng, Timothy D. Veenstra, Judith Frydman, Steven E. Artandi

Cell. Author manuscript; available in PMC 2015 Dec 4.

Published in final edited form as: Cell. 2014 Dec 4; 159(6): 1389–1403. Published online 2014 Nov 20. doi: 10.1016/j.cell.2014.10.059

PMCID:: PMC4329143

Abstract Article PDF–1.4M

Select item 364210414.

The Novel Ubiquitin Ligase Complex, SCF^Fbxw4, Interacts with the COP9 Signalosome in an F-Box Dependent Manner, Is Mutated, Lost and Under-Expressed in Human Cancers

William W. Lockwood, Sahiba K. Chandel, Greg L. Stewart, Hediye Erdjument-Bromage, Levi J. Beverly

PLoS One. 2013; 8(5): e63610. Published online 2013 May 2. doi: 10.1371/journal.pone.0063610

PMCID:: PMC3642104

Abstract Article PDF–1.7M

Select item 844035715.

The von Hippel–Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases

Gaël K. Scholtès, Aubrey M. Sawyer, Cristina C. Vaca, Isabelle Clerc, Meejeon Roh, Chisu Song, Richard T. D’Aquila

Transl Res. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Transl Res. 2021 Nov; 237: 1–15. Published online 2021 May 15. doi: 10.1016/j.trsl.2021.05.002

PMCID:: PMC8440357

Abstract Article PDF–628K

Select item 282439016.

BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

Seongjin Seo, Lisa M. Baye, Nathan P. Schulz, John S. Beck, Qihong Zhang, Diane C. Slusarski, Val C. Sheffield

Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4): 1488–1493. Published online 2010 Jan 6. doi: 10.1073/pnas.0910268107

PMCID:: PMC2824390

Abstract Article PDF–1009K

Select item 856535217.

Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation

Manuela Lanzafame, Giulia Branca, Claudia Landi, Mingyue Qiang, Bruno Vaz, Tiziana Nardo, Debora Ferri, Manuela Mura, Sebastian Iben, Miria Stefanini, Fiorenzo A Peverali, Luca Bini, Donata Orioli

Nucleic Acids Res. 2021 Nov 8; 49(19): 10911–10930. Published online 2021 Sep 28. doi: 10.1093/nar/gkab819

PMCID:: PMC8565352

Abstract Article PDF–7.2M

Select item 447540218.

Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase

Yu Zhao, Mona C Majid, Jennifer M Soll, Joshua R Brickner, Sebastian Dango, Nima Mosammaparast

EMBO J. 2015 Jun 12; 34(12): 1687–1703. Published online 2015 May 5. doi: 10.15252/embj.201490497

PMCID:: PMC4475402

Abstract Article PDF–2.2M

Select item 630576619.

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx

Christine D. Landsberg, Dominik A. Megger, Dominik Hotter, Meike U. Rückborn, Mareike Eilbrecht, Jassin Rashidi-Alavijeh, Sebastian Howe, Stefan Heinrichs, Daniel Sauter, Barbara Sitek, Vu Thuy Khanh Le-Trilling, Mirko Trilling

Front Immunol. 2018; 9: 2978. Published online 2018 Dec 19. doi: 10.3389/fimmu.2018.02978

PMCID:: PMC6305766

Abstract Article PDF–4.3M

Select item 262100420.

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

Marilyn Goudreault, Lisa M. D’Ambrosio, Michelle J. Kean, Michael J. Mullin, Brett G. Larsen, Amy Sanchez, Sidharth Chaudhry, Ginny I. Chen, Frank Sicheri, Alexey I. Nesvizhskii, Ruedi Aebersold, Brian Raught, Anne-Claude Gingras

Mol Cell Proteomics. 2009 Jan; 8(1): 157–171. doi: 10.1074/mcp.M800266-MCP200