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Select item 36771381.

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia

S H Oram, J Thoms, J I Sive, F J Calero-Nieto, S J Kinston, J Schütte, K Knezevic, R B Lock, J E Pimanda, B Göttgens

Leukemia. 2013 Jun; 27(6): 1348–1357. Prepublished online 2013 Jan 10. Published online 2013 Feb 1. doi: 10.1038/leu.2013.2

PMCID:: PMC3677138

Abstract Article PDF–1.9M

Select item 3630062.

The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein.

E A McGuire, R D Hockett, K M Pollock, M F Bartholdi, S J O'Brien, S J Korsmeyer

Mol Cell Biol. 1989 May; 9(5): 2124–2132. doi: 10.1128/mcb.9.5.2124

PMCID:: PMC363006

Summary Page Browse PDF–2.1M

Select item 3603233.

Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma.

E A McGuire, C E Rintoul, G M Sclar, S J Korsmeyer

Mol Cell Biol. 1992 Sep; 12(9): 4186–4196. doi: 10.1128/mcb.12.9.4186

PMCID:: PMC360323

Summary Page Browse PDF–3.7M

Select item 67938044.

Expression of LIM Protein Genes Lmo1, Lmo2, andLmo3 in Adult Mouse Hippocampus and Other Forebrain Regions: Differential Regulation by Seizure Activity

G. L. Hinks, B. Shah, S. J. French, L. S. Campos, K. Staley, J. Hughes, M. V. Sofroniew

J Neurosci. 1997 Jul 15; 17(14): 5549–5559. doi: 10.1523/JNEUROSCI.17-14-05549.1997

PMCID:: PMC6793804

Abstract Article PDF–2.1M

Select item 42704385.

SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells

Bastien Gerby, Cedric S. Tremblay, Mathieu Tremblay, Shanti Rojas-Sutterlin, Sabine Herblot, Josée Hébert, Guy Sauvageau, Sébastien Lemieux, Eric Lécuyer, Diogo F. T. Veiga, Trang Hoang

PLoS Genet. 2014 Dec; 10(12): e1004768. Published online 2014 Dec 18. doi: 10.1371/journal.pgen.1004768

PMCID:: PMC4270438

Abstract Article PDF–3.3M

Select item 11698416.

An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice.

P D Aplan, C A Jones, D S Chervinsky, X Zhao, M Ellsworth, C Wu, E A McGuire, K W Gross

EMBO J. 1997 May 1; 16(9): 2408–2419. doi: 10.1093/emboj/16.9.2408

PMCID:: PMC1169841

Summary PDF–437K

Select item 3505627.

Null Mutation of the Lmo4 Gene or a Combined Null Mutation of the Lmo1/Lmo3 Genes Causes Perinatal Lethality, and Lmo4 Controls Neural Tube Development in Mice

E. Tse, A. J. H. Smith, S. Hunt, I. Lavenir, A. Forster, A. J. Warren, G. Grutz, L. Foroni, M. B. L. Carlton, W. H. Colledge, T. Boehm, T. H. Rabbitts

Mol Cell Biol. 2004 Mar; 24(5): 2063–2073. doi: 10.1128/MCB.24.5.2063-2073.2004

PMCID:: PMC350562

Abstract Article PDF–896K

Select item 516608.

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13.

T Boehm, L Foroni, Y Kaneko, M F Perutz, T H Rabbitts

Proc Natl Acad Sci U S A. 1991 May 15; 88(10): 4367–4371. doi: 10.1073/pnas.88.10.4367

PMCID:: PMC51660

Summary Page Browse PDF–1.3M

Select item 515669.

A simple technique for generating probes for RNA in situ hybridization: an adjunct to genome mapping exemplified by the RAG-1/RAG-2 gene cluster.

T Boehm, R Gonzalez-Sarmiento, M Kennedy, T H Rabbitts

Proc Natl Acad Sci U S A. 1991 May 1; 88(9): 3927–3931. doi: 10.1073/pnas.88.9.3927

PMCID:: PMC51566

Summary Page Browse PDF–1.7M

Select item 287864810.

Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes

Mathieu Tremblay, Cédric S. Tremblay, Sabine Herblot, Peter D. Aplan, Josée Hébert, Claude Perreault, Trang Hoang

Genes Dev. 2010 Jun 1; 24(11): 1093–1105. doi: 10.1101/gad.1897910

PMCID:: PMC2878648

Abstract Article PDF–1.1M

Select item 8433511.

Disordered T-Cell Development and T-Cell Malignancies in SCL LMO1 Double-Transgenic Mice: Parallels with E2A-Deficient Mice

David S. Chervinsky, Xian-Feng Zhao, Du H. Lam, MaryKay Ellsworth, Kenneth W. Gross, Peter D. Aplan

Mol Cell Biol. 1999 Jul; 19(7): 5025–5035. doi: 10.1128/mcb.19.7.5025

PMCID:: PMC84335

Abstract Article PDF–3.2M

Select item 768786012.

Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production

Miguel Turrero García, José-Manuel Baizabal, Diana N. Tran, Rui Peixoto, Wengang Wang, Yajun Xie, Manal A. Adam, Lauren A. English, Christopher M. Reid, Salvador I. Brito, Matthew A. Booker, Michael Y. Tolstorukov, Corey C. Harwell

Development. 2020 Nov 15; 147(22): dev187526. Published online 2020 Nov 16. doi: 10.1242/dev.187526