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Select item 56812711.

Amino acid sensing in hypothalamic tanycytes via umami taste receptors

Greta Lazutkaite, Alice Soldà, Kristina Lossow, Wolfgang Meyerhof, Nicholas Dale

Mol Metab. 2017 Nov; 6(11): 1480–1492. Published online 2017 Sep 14. doi: 10.1016/j.molmet.2017.08.015

PMCID:: PMC5681271

Abstract Article PDF–4.7M

Select item 42549582.

Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon

Derek M. Kendig, Norman R. Hurst, Zachary L. Bradley, Sunila Mahavadi, John F. Kuemmerle, Vijay Lyall, John DeSimone, Karnam S. Murthy, John R. Grider

Am J Physiol Gastrointest Liver Physiol. 2014 Dec 1; 307(11): G1100–G1107. Published online 2014 Oct 16. doi: 10.1152/ajpgi.00251.2014

PMCID:: PMC4254958

Abstract Article

Select item 36248633.

Taste responses in mice lacking taste receptor subunit T1R1

Yoko Kusuhara, Ryusuke Yoshida, Tadahiro Ohkuri, Keiko Yasumatsu, Anja Voigt, Sandra Hübner, Katsumasa Maeda, Ulrich Boehm, Wolfgang Meyerhof, Yuzo Ninomiya

J Physiol. 2013 Apr 1; 591(Pt 7): 1967–1985. Published online 2013 Jan 21. doi: 10.1113/jphysiol.2012.236604

PMCID:: PMC3624863

Abstract Article PDF–1.5M

Select item 37499154.

The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy

Eric M. Wauson, Elma Zaganjor, A-Young Lee, Marcy L. Guerra, Anwesha B. Ghosh, Angie L. Bookout, Chris P. Chambers, Arif Jivan, Kathleen McGlynn, Michele R. Hutchison, Ralph J. Deberardinis, Melanie H. Cobb

Mol Cell. Author manuscript; available in PMC 2013 Sep 28.

Published in final edited form as: Mol Cell. 2012 Sep 28; 47(6): 851–862. Published online 2012 Sep 6. doi: 10.1016/j.molcel.2012.08.001

PMCID:: PMC3749915

Abstract Article PDF–2.1M

Select item 35902635.

Amino acid regulation of autophagy through the GPCR TAS1R1-TAS1R3

Eric M. Wauson, Elma Zaganjor, Melanie H. Cobb

Autophagy. 2013 Mar 1; 9(3): 418–419. doi: 10.4161/auto.22911

PMCID:: PMC3590263

Abstract Article PDF–712K

Select item 35665116.

Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion

Kristian Daly, Miran Al-Rammahi, Andrew Moran, Marco Marcello, Yuzo Ninomiya, Soraya P. Shirazi-Beechey

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1; 304(3): G271–G282. Published online 2012 Nov 29. doi: 10.1152/ajpgi.00074.2012

PMCID:: PMC3566511

Abstract Article

Select item 66051457.

Transsynaptic Tracing from Taste Receptor Cells Reveals Local Taste Receptor Gene Expression in Gustatory Ganglia and Brain

Anja Voigt, Juliane Bojahr, Masataka Narukawa, Sandra Hübner, Ulrich Boehm, Wolfgang Meyerhof

J Neurosci. 2015 Jul 1; 35(26): 9717–9729. doi: 10.1523/JNEUROSCI.0381-15.2015

PMCID:: PMC6605145

Abstract Article PDF–4.5M

Select item 60322988.

Taste sensitivity to a mixture of monosodium glutamate and inosine 5′-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor

Ginger D. Blonde, Susan P. Travers, Alan C. Spector

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1; 314(6): R802–R810. Published online 2018 Feb 14. doi: 10.1152/ajpregu.00352.2017

PMCID:: PMC6032298

Abstract Article

Select item 58635539.

Phosphorus Taste Involves T1R2 and T1R3

Michael G. Tordoff

Chem Senses. 2017 Jun; 42(5): 425–433. Published online 2017 Apr 5. doi: 10.1093/chemse/bjx019

PMCID:: PMC5863553

Abstract Article PDF–4.6M

Select item 439853510.

Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice

Keiko Yasumatsu, Tomohiro Manabe, Ryusuke Yoshida, Ken Iwatsuki, Hisayuki Uneyama, Ichiro Takahashi, Yuzo Ninomiya

J Physiol. 2015 Feb 15; 593(Pt 4): 1021–1034. Published online 2015 Jan 22. doi: 10.1113/jphysiol.2014.284703

PMCID:: PMC4398535

Abstract Article PDF–515K

Select item 365579311.

Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart

Simon R. Foster, Enzo R. Porrello, Brooke Purdue, Hsiu-Wen Chan, Anja Voigt, Sabine Frenzel, Ross D. Hannan, Karen M. Moritz, David G. Simmons, Peter Molenaar, Eugeni Roura, Ulrich Boehm, Wolfgang Meyerhof, Walter G. Thomas

PLoS One. 2013; 8(5): e64579. Published online 2013 May 15. doi: 10.1371/journal.pone.0064579

PMCID:: PMC3655793

Abstract Article PDF–2.0M

Select item 451799712.

Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells

Eric M. Wauson, Marcy L. Guerra, Julia Dyachok, Kathleen McGlynn, Jennifer Giles, Elliott M. Ross, Melanie H. Cobb

Mol Endocrinol. 2015 Aug; 29(8): 1114–1122. Published online 2015 Jul 13. doi: 10.1210/ME.2014-1181

PMCID:: PMC4517997

Abstract Article

Select item 387354613.

Two Distinct Determinants of Ligand Specificity in T1R1/T1R3 (the Umami Taste Receptor)

Yasuka Toda, Tomoya Nakagita, Takashi Hayakawa, Shinji Okada, Masataka Narukawa, Hiroo Imai, Yoshiro Ishimaru, Takumi Misaka

J Biol Chem. 2013 Dec 27; 288(52): 36863–36877. Published online 2013 Nov 8. doi: 10.1074/jbc.M113.494443

PMCID:: PMC3873546

Abstract Article PDF–5.0M

Select item 330355114.

Expression of Tas1 Taste Receptors in Mammalian Spermatozoa: Functional Role of Tas1r1 in Regulating Basal Ca²⁺ and cAMP Concentrations in Spermatozoa

Dorke Meyer, Anja Voigt, Patricia Widmayer, Heike Borth, Sandra Huebner, Andreas Breit, Susan Marschall, Martin Hrabé de Angelis, Ulrich Boehm, Wolfgang Meyerhof, Thomas Gudermann, Ingrid Boekhoff

PLoS One. 2012; 7(2): e32354. Published online 2012 Feb 29. doi: 10.1371/journal.pone.0032354

PMCID:: PMC3303551

Abstract Article PDF–2.0M

Select item 382088215.

Artificial Sweeteners Stimulate Adipogenesis and Suppress Lipolysis Independently of Sweet Taste Receptors

Becky R. Simon, Sebastian D. Parlee, Brian S. Learman, Hiroyuki Mori, Erica L. Scheller, William P. Cawthorn, Xiaomin Ning, Katherine Gallagher, Björn Tyrberg, Fariba M. Assadi-Porter, Charles R. Evans, Ormond A. MacDougald

J Biol Chem. 2013 Nov 8; 288(45): 32475–32489. Published online 2013 Sep 24. doi: 10.1074/jbc.M113.514034

PMCID:: PMC3820882

Abstract Article PDF–2.4M

Select item 338182216.

Umami taste in mice uses multiple receptors and transduction pathways

Keiko Yasumatsu, Yoko Ogiwara, Shingo Takai, Ryusuke Yoshida, Ken Iwatsuki, Kunio Torii, Robert F Margolskee, Yuzo Ninomiya

J Physiol. 2012 Mar 1; 590(Pt 5): 1155–1170. Published online 2011 Dec 19. doi: 10.1113/jphysiol.2011.211920

PMCID:: PMC3381822

Abstract Article PDF–1.5M

Select item 363821117.

High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4

Xia Li, Masashi Inoue, Danielle R. Reed, Taufiqul Huque, Ralph B. Puchalski, Michael G. Tordoff, Yuzo Ninomiya, Gary K. Beauchamp, Alexander A. Bachmanov

Mamm Genome. Author manuscript; available in PMC 2013 Apr 29.

Published in final edited form as: Mamm Genome. 2001 Jan; 12(1): 13–16. doi: 10.1007/s003350010236

PMCID:: PMC3638211

Abstract Article PDF–1.6M

Select item 417816218.

Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system

Juraj Koudelka, Jacqueline M Horn, Chinnavuth Vatanashevanopakorn, Liliana Minichiello

Neural Dev. 2014; 9: 21. Published online 2014 Sep 26. doi: 10.1186/1749-8104-9-21

PMCID:: PMC4178162

Abstract Article PDF–3.0M

Select item 1013156019.

A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells

Makoto Ohmoto, Masafumi Jyotaki, Karen K. Yee, Ichiro Matsumoto

eNeuro. 2023 Apr; 10(4): ENEURO.0236-22.2023. Prepublished online 2023 Apr 12. Published online 2023 Apr 21. doi: 10.1523/ENEURO.0236-22.2023

PMCID:: PMC10131560

Abstract Article PDF–6.9M

Select item 364480120.

Positional cloning of the mouse saccharin preference (Sac) locus

Alexander A. Bachmanov, Xia Li, Danielle R. Reed, Jeffery D. Ohmen, Shanru Li, Zhenyu Chen, Michael G. Tordoff, Pieter J. de Jong, Chenyan Wu, David B. West, Alu Chatterjee, David A. Ross, Gary K. Beauchamp

Chem Senses. Author manuscript; available in PMC 2013 May 6.

Published in final edited form as: Chem Senses. 2001 Sep; 26(7): 925–933. doi: 10.1093/chemse/26.7.925