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Select item 109298391.

Pan-cancer analysis of NUDT21 and its effect on the proliferation of human head and neck squamous cell carcinoma

Wenjing Liu, Yingna Pang, Xiaolu Yu, Doudou Lu, Yating Yang, Fandi Meng, Chengbi Xu, Ling Yuan, Yi Nan

Aging (Albany NY) 2024 Feb 28; 16(4): 3363–3385. Published online 2024 Feb 12. doi: 10.18632/aging.205539

PMCID:: PMC10929839

Abstract Article PDF–5.7M

Select item 108452632.

Predictive Value of CFIm25 Expression in Peripheral Blood Monocytes for Coronary Atherosclerosis

Meng Liu, Xiaoxiao Chen, Zhan Gu, Hao He, Mingyue Chen, Lin Kuai, Zhiqiang Jia, Yi Li, Yizhou Chen, Mei Hong, Fangping Xiao

Int J Med Sci. 2024; 21(3): 562–570. Published online 2024 Jan 20. doi: 10.7150/ijms.91148

PMCID:: PMC10845263

Abstract Article PDF–1.8M

Select item 99256143.

The emerging roles of CFIm25 (NUDT21/CPSF5) in human biology and disease

Chioniso Patience Masamha

Wiley Interdiscip Rev RNA. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Wiley Interdiscip Rev RNA. 2023 May-Jun; 14(3): e1757. Published online 2022 Aug 14. doi: 10.1002/wrna.1757

PMCID:: PMC9925614

Abstract Article PDF–1.0M

Select item 73605884.

Involved microRNAs in alternative polyadenylation intervene in breast cancer via regulation of cleavage factor “CFIm25”

Mona Tamaddon, Gelareh Shokri, Seyed Mohammad Ali Hosseini Rad, Iman Rad, Àmirnader Emami Razavi, Fatemeh Kouhkan

Sci Rep. 2020; 10: 11608. Published online 2020 Jul 14. doi: 10.1038/s41598-020-68406-3

PMCID:: PMC7360588

Abstract Article PDF–3.4M

Select item 60958005.

Suppression of Cleavage Factor Im 25 Promotes the Proliferation of Lung Cancer Cells through Alternative Polyadenylation

Jingjing Huang, Tingting Weng, Junsuk Ko, Ning-yuan Chen, Yu Xiang, Kelly Volcik, Leng Han, Michael R. Blackburn, Xiang Lu

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Sep 5.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 5; 503(2): 856–862. Published online 2018 Jun 23. doi: 10.1016/j.bbrc.2018.06.087

PMCID:: PMC6095800

Abstract Article PDF–565K

Select item 24254706.

Crystal structure of the 25 kDa subunit of human cleavage factor I_m

Molly Coseno, Georges Martin, Christopher Berger, Gregory Gilmartin, Walter Keller, Sylvie Doublié

Nucleic Acids Res. 2008 Jun; 36(10): 3474–3483. Published online 2008 Apr 29. doi: 10.1093/nar/gkn079

PMCID:: PMC2425470

Abstract Article PDF–753K

Select item 107766987.

NUDT21 interacts with NDUFS2 to activate the PI3K/AKT pathway and promotes pancreatic cancer pathogenesis

Xiao-Dong Huang, Yong-Wei Chen, Lv Tian, Li Du, Xiao-Chen Cheng, Yu-Xin Lu, Dong-Dong Lin, Feng-Jun Xiao

J Cancer Res Clin Oncol. 2024; 150(1): 8. Published online 2024 Jan 9. doi: 10.1007/s00432-023-05540-1

PMCID:: PMC10776698

Abstract Article PDF–14M

Select item 105617248.

Alternative polyadenylation reprogramming of MORC2 induced by NUDT21 loss promotes KIRC carcinogenesis

Yuqin Tan, Tong Zheng, Zijun Su, Min Chen, Suxiang Chen, Rui Zhang, Ruojiao Wang, Ke Li, Ning Na

JCI Insight. 2023 Sep 22; 8(18): e162893. Published online 2023 Sep 22. doi: 10.1172/jci.insight.162893

PMCID:: PMC10561724

Abstract Article PDF–14M

Select item 104037309.

PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation

Wen-Liang Guan, Lei-Lei Jiang, Xiao-Fang Yin, Hong-Yu Hu

J Biol Chem. 2023 Aug; 299(8): 105019. Published online 2023 Jul 7. doi: 10.1016/j.jbc.2023.105019

PMCID:: PMC10403730

Abstract Article PDF–4.6M

Select item 1032596010.

Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection

Charlotte Luchsinger, KyeongEun Lee, Gonzalo A. Mardones, Vineet N. KewalRamani, Felipe Diaz-Griffero

Sci Rep. 2023; 13: 10974. Published online 2023 Jul 6. doi: 10.1038/s41598-023-37364-x

PMCID:: PMC10325960

Abstract Article PDF–7.1M

Select item 961150611.

NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia

Matthew T. Witkowski, Soobeom Lee, Eric Wang, Anna K. Lee, Alexis Talbot, Chao Ma, Nikolaos Tsopoulidis, Justin Brumbaugh, Yaqi Zhao, Kathryn G. Roberts, Simon J. Hogg, Sofia Nomikou, Yohana Ghebrechristos, Palaniraja Thandapani, Charles G. Mullighan, Konrad Hochedlinger, Weiqiang Chen, Omar Abdel-Wahab, Justin Eyquem, Iannis Aifantis

Nat Immunol. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Nat Immunol. 2022 Oct; 23(10): 1424–1432. Published online 2022 Sep 22. doi: 10.1038/s41590-022-01314-y

PMCID:: PMC9611506

Abstract Article PDF–5.2M

Select item 704171412.

Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylation

Tingting Weng, Jingjing Huang, Eric J. Wagner, Junsuk Ko, Minghua Wu, Nancy E. Wareing, Yu Xiang, Ning-Yuan Chen, Ping Ji, Jose G. Molina, Kelly A. Volcik, Leng Han, Maureen D. Mayes, Michael R. Blackburn, Shervin Assassi

J Exp Med. 2020 Feb 3; 217(2): e20181384. Published online 2019 Nov 22. doi: 10.1084/jem.20181384

PMCID:: PMC7041714

Abstract Article PDF–3.1M

Select item 653313113.

Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients

Yuan Chu, Nathan Elrod, Chaojie Wang, Lei Li, Tao Chen, Andrew Routh, Zheng Xia, Wei Li, Eric J. Wagner, Ping Ji

Oncogene. Author manuscript; available in PMC 2019 May 23.

Published in final edited form as: Oncogene. 2019 May; 38(21): 4154–4168. Published online 2019 Jan 31. doi: 10.1038/s41388-019-0714-9

PMCID:: PMC6533131

Abstract Article PDF–1.5M

Select item 648429314.

The role of NUDT21 in microRNA‐binging sites of EZH2 gene increases the of risk preeclampsia

Xiao Lang, Wenxia Zhao, Ding Huang, Wei Liu, Hong Shen, Liang Xu, Shan Xu, Yongfang Huang, Weiwei Cheng

J Cell Mol Med. 2019 May; 23(5): 3202–3213. Published online 2019 Mar 18. doi: 10.1111/jcmm.14179

PMCID:: PMC6484293

Abstract Article PDF–1.3M

Select item 541128315.

RNAcompete methodology and application to determine sequence preferences of unconventional RNA-binding proteins

Debashish Ray, Kevin C.H. Ha, Kate Nie, Hong Zheng, Timothy R. Hughes, Quaid D. Morris

Methods. Author manuscript; available in PMC 2018 Apr 15.

Published in final edited form as: Methods. 2017 Apr 15; 118-119: 3–15. Published online 2016 Dec 10. doi: 10.1016/j.ymeth.2016.12.003

PMCID:: PMC5411283

Abstract Article PDF–1.2M

Select item 458639116.

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation

Vincenzo A Gennarino, Callison E Alcott, Chun-An Chen, Arindam Chaudhury, Madelyn A Gillentine, Jill A Rosenfeld, Sumit Parikh, James W Wheless, Elizabeth R Roeder, Dafne DG Horovitz, Erin K Roney, Janice L Smith, Sau W Cheung, Wei Li, Joel R Neilson, Christian P Schaaf, Huda Y Zoghbi

eLife. 2015; 4: e10782. Published online 2015 Aug 27. doi: 10.7554/eLife.10782

PMCID:: PMC4586391

Abstract Article PDF–2.3M

Select item 289049317.

Structural basis of UGUA recognition by the Nudix protein CFI_m25 and implications for a regulatory role in mRNA 3′ processing

Qin Yang, Gregory M. Gilmartin, Sylvie Doublié

Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22): 10062–10067. Published online 2010 May 17. doi: 10.1073/pnas.1000848107

PMCID:: PMC2890493

Abstract Article PDF–1.8M

Select item 166974318.

Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs

Tomohiro Kubo, Tadashi Wada, Yuki Yamaguchi, Akira Shimizu, Hiroshi Handa

Nucleic Acids Res. 2006 Dec; 34(21): 6264–6271. Published online 2006 Nov 10. doi: 10.1093/nar/gkl794

PMCID:: PMC1669743

Abstract Article PDF–320K

Select item 717643319.

Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

Callison E Alcott, Hari Krishna Yalamanchili, Ping Ji, Meike E van der Heijden, Alexander Saltzman, Nathan Elrod, Ai Lin, Mei Leng, Bhoomi Bhatt, Shuang Hao, Qi Wang, Afaf Saliba, Jianrong Tang, Anna Malovannaya, Eric J Wagner, Zhandong Liu, Huda Y Zoghbi

eLife. 2020; 9: e50895. Published online 2020 Apr 22. doi: 10.7554/eLife.50895

PMCID:: PMC7176433

Abstract Article PDF–3.3M

Select item 683128820.

NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation

Ming Xiong, Liang Chen, Lijie Zhou, Yong Ding, Gallina Kazobinka, Zhaohui Chen, Teng Hou

Theranostics. 2019; 9(24): 7156–7167. Published online 2019 Sep 23. doi: 10.7150/thno.36030

PMCID:: PMC6831288

Abstract Article PDF–2.9M

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