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Select item 91697081.

A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives

Yi Li, Lina Wei, Marie-Charlotte Meinsohn, Rana Suliman, Maeva Chauvin, Jim Berstler, Kate Hartland, Mark M. Jensen, Natalie A. Sicher, Nicholas Nagykery, Patricia K. Donahoe, David Pepin

Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2122512119. Published online 2022 Apr 5. doi: 10.1073/pnas.2122512119

PMCID:: PMC9169708

Abstract Article PDF–2.0M

Select item 81579662.

Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries

Marie-Charlotte Meinsohn, Hatice D. Saatcioglu, Lina Wei, Yi Li, Heiko Horn, Maeva Chauvin, Motohiro Kano, Ngoc Minh Phuong Nguyen, Nicholas Nagykery, Aki Kashiwagi, Wesley R. Samore, Dan Wang, Esther Oliva, Guangping Gao, Mary E. Morris, Patricia K. Donahoe, David Pépin

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2100920118. Published online 2021 May 12. doi: 10.1073/pnas.2100920118

PMCID:: PMC8157966

Abstract Article PDF–3.7M

Select item 106049163.

Oocyte-Specific Deletion of Slc6a9 Encoding the GLYT1 Glycine Transporter Eliminates Glycine Transport in Mouse Preimplantation Embryos and Their Ability to Counter Hypertonic Stress

Allison K. Tscherner, Taylor McClatchie, Gracia Kaboba, Detlev Boison, Jay M. Baltz

Cells. 2023 Oct; 12(20): 2500. Published online 2023 Oct 21. doi: 10.3390/cells12202500

PMCID:: PMC10604916

Abstract Article PDF–1.9M

Select item 101068424.

iCre recombinase expressed in the anti-Müllerian hormone receptor 2 gene causes global genetic modification in the mouse

Mackenzie J Dickson, Artiom Gruzdev, Francesco J DeMayo

Biol Reprod. 2023 Apr; 108(4): 575–583. Published online 2023 Jan 31. doi: 10.1093/biolre/ioad012

PMCID:: PMC10106842

Abstract Article PDF–1.2M

Select item 97793495.

Role of EZH2 in Uterine Gland Development

Nan Ni, Frank L. Jalufka, Xin Fang, Dylan A. McCreedy, Qinglei Li

Int J Mol Sci. 2022 Dec; 23(24): 15665. Published online 2022 Dec 10. doi: 10.3390/ijms232415665

PMCID:: PMC9779349

Abstract Article PDF–6.7M

Select item 95769166.

Loss of Anti-Müllerian Hormone Signaling in Mice Affects Trabecular Bone Mass in a Sex- and Age-Dependent Manner

Christiane van As, Marijke Koedam, Anke McLuskey, Piet Kramer, Najiba Lahlou, Bram C J van der Eerden, Jenny A Visser

Endocrinology. 2022 Nov; 163(11): bqac157. Published online 2022 Sep 26. doi: 10.1210/endocr/bqac157

PMCID:: PMC9576916

Abstract Article

Select item 78070747.

A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation

Marie-Charlotte Meinsohn, Camilla H. K. Hughes, Anthony Estienne, Hatice D. Saatcioglu, David Pépin, Raj Duggavathi, Bruce D. Murphy

Sci Rep. 2021; 11: 1079. Published online 2021 Jan 13. doi: 10.1038/s41598-020-80178-4

PMCID:: PMC7807074

Abstract Article PDF–10M

Select item 74924058.

Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells

Cheng Wei, Yibin Pan, Yinli Zhang, Yongdong Dai, Lingling Jiang, Libing Shi, Weijie Yang, Shiqian Xu, Yingyi Zhang, Wenzhi Xu, Yanling Zhang, Xiaona Lin, Songying Zhang

Cell Death Dis. 2020 Sep; 11(9): 755. Published online 2020 Sep 15. doi: 10.1038/s41419-020-02956-2

Correction in:: Cell Death Dis. 2020 Oct; 11(10): 935.

PMCID:: PMC7492405

Abstract Article PDF–3.3M

Select item 74033479.

Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman’s Syndrome via HIF1α-Dependent Angiogenesis

Mira Park, Seok-Ho Hong, So Hee Park, Yeon Sun Kim, Seung Chel Yang, Hye-Ryun Kim, Songmi Noh, Sunghun Na, Hyung Keun Lee, Hyunjung J. Lim, Sang Woo Lyu, Haengseok Song

Mol Ther. 2020 Aug 5; 28(8): 1818–1832. Published online 2020 May 20. doi: 10.1016/j.ymthe.2020.05.015

PMCID:: PMC7403347

Abstract Article PDF–4.8M

Select item 729801610.

Non-canonical WNT5a regulates Epithelial-to-Mesenchymal Transition in the mouse ovarian surface epithelium

Atefeh Abedini, Céline Sayed, Lauren E. Carter, Derek Boerboom, Barbara C. Vanderhyden

Sci Rep. 2020; 10: 9695. Published online 2020 Jun 16. doi: 10.1038/s41598-020-66559-9

PMCID:: PMC7298016

Abstract Article PDF–6.2M

Select item 665024711.

Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility

Hatice Duygu Saatcioglu, Motohiro Kano, Heiko Horn, Lihua Zhang, Wesley Samore, Nicholas Nagykery, Marie-Charlotte Meinsohn, Minsuk Hyun, Rana Suliman, Joy Poulo, Jennifer Hsu, Caitlin Sacha, Dan Wang, Guangping Gao, Kasper Lage, Esther Oliva, Mary E Morris Sabatini, Patricia K Donahoe, David Pépin

eLife. 2019; 8: e46349. Published online 2019 Jun 24. doi: 10.7554/eLife.46349

PMCID:: PMC6650247

Abstract Article PDF–5.3M

Select item 656185812.

Progesterone receptor membrane component 1 and 2 regulate granulosa cell mitosis and survival through a NF_ΚB-dependent mechanism

John J Peluso, Cindy A Pru, Xiufang Liu, Nicole C Kelp, James K Pru

Biol Reprod. 2019 Jun; 100(6): 1571–1580. Published online 2019 Mar 16. doi: 10.1093/biolre/ioz043

PMCID:: PMC6561858

Abstract Article PDF–1.5M

Select item 624838813.

Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg

Xinye Wang, Priya Mittal, Carlos A Castro, Gabriel Rajkovic, Aleksandar Rajkovic

Biol Reprod. 2017 Dec; 97(6): 822–834. Published online 2017 Nov 8. doi: 10.1093/biolre/iox143

PMCID:: PMC6248388

Abstract Article PDF–2.8M

Select item 556639714.

Juxtacrine Activity of Estrogen Receptor α in Uterine Stromal Cells is Necessary for Estrogen-Induced Epithelial Cell Proliferation

Wipawee Winuthayanon, Sydney L. Lierz, Karena C. Delarosa, Skylar R. Sampels, Lauren J. Donoghue, Sylvia C. Hewitt, Kenneth S. Korach

Sci Rep. 2017; 7: 8377. Published online 2017 Aug 21. doi: 10.1038/s41598-017-07728-1

PMCID:: PMC5566397

Abstract Article PDF–8.4M

Select item 548299315.

Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels

Shi Yin, Xiaohua Jiang, Hanwei Jiang, Qian Gao, Fang Wang, Suixing Fan, Teka Khan, Nazish Jabeen, Manan Khan, Asim Ali, Peng Xu, Tej K. Pandita, Heng-Yu Fan, Yuanwei Zhang, Qinghua Shi

Development. 2017 Jun 15; 144(12): 2165–2174. doi: 10.1242/dev.149518

PMCID:: PMC5482993

Abstract Article

Select item 532864316.

Overactivation of Hedgehog Signaling in the Developing Müllerian Duct Interferes with Duct Regression in Males and Causes Subfertility

Fernando F. Migone, Pei-hsuan Hung, Robert G. Cowan, Vimal Selvaraj, Susan S. Suarez, Susan M. Quirk

Reproduction. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Reproduction. 2017 Apr; 153(4): 481–492. Published online 2017 Jan 25. doi: 10.1530/REP-16-0562

PMCID:: PMC5328643

Abstract Article PDF–3.9M

Select item 504118917.

Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve

Z Dong, M Huang, Z Liu, P Xie, Y Dong, X Wu, Z Qu, B Shen, X Huang, T Zhang, J Li, J Liu, T Yanase, C Zhou, Y Xu

Cell Death Differ. 2016 Oct; 23(10): 1602–1614. Published online 2016 May 20. doi: 10.1038/cdd.2016.47

PMCID:: PMC5041189

Abstract Article PDF–4.3M

Select item 486116818.

Deletion of Arid1a in Reproductive Tract Mesenchymal Cells Reduces Fertility in Female Mice

Xiyin Wang, Shikha Khatri, Russell Broaddus, Zhong Wang, Shannon M. Hawkins

Biol Reprod. 2016 Apr; 94(4): 93. Published online 2016 Mar 9. doi: 10.1095/biolreprod.115.133637

PMCID:: PMC4861168

Abstract Article PDF–1.8M

Select item 477653419.

In vivo imaging reveals an essential role of vasoconstriction in rupture of the ovarian follicle at ovulation

Fernando F. Migone, Robert G. Cowan, Rebecca M. Williams, Kiersten J. Gorse, Warren R. Zipfel, Susan M. Quirk

Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2294–2299. Published online 2016 Feb 3. doi: 10.1073/pnas.1512304113

PMCID:: PMC4776534

Abstract Article PDF–1.2M

Select item 471872820.

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

Wipawee Winuthayanon, Miranda L Bernhardt, Elizabeth Padilla-Banks, Page H Myers, Matthew L Edin, Fred B Lih, Sylvia C Hewitt, Kenneth S Korach, Carmen J Williams

eLife. 2015; 4: e10453. Published online 2015 Dec 1. doi: 10.7554/eLife.10453