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Select item 63275091.

RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment

Shi Chen, Jiaqiang Zhang, Jiangzhi Chen, Yaodong Wang, Songqiang Zhou, Long Huang, Yannan Bai, Chenghong Peng, Baiyong Shen, Huixing Chen, Yifeng Tian

J Exp Clin Cancer Res. 2019; 38: 15. Published online 2019 Jan 10. doi: 10.1186/s13046-018-0986-x

PMCID:: PMC6327509

Abstract Article PDF–3.0M

Select item 41229632.

Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking

Akinori Yamasaki, Taichi Hara, Ikuko Maejima, Miyuki Sato, Katsuya Sato, Ken Sato

Sci Rep. 2014; 4: 5973. Published online 2014 Aug 6. doi: 10.1038/srep05973

PMCID:: PMC4122963

Abstract Article PDF–2.2M

Select item 35047763.

Retention in Endoplasmic Reticulum 1 (RER1) Modulates Amyloid-β (Aβ) Production by Altering Trafficking of γ-Secretase and Amyloid Precursor Protein (APP)

Hyo-Jin Park, Daniil Shabashvili, Michael D. Nekorchuk, Eva Shyqyriu, Joo In Jung, Thomas B. Ladd, Brenda D. Moore, Kevin M. Felsenstein, Todd E. Golde, Seong-Hun Kim

J Biol Chem. 2012 Nov 23; 287(48): 40629–40640. Published online 2012 Oct 5. doi: 10.1074/jbc.M112.418442

PMCID:: PMC3504776

Abstract Article PDF–2.2M

Select item 19780844.

Endoplasmic reticulum retention of the γ-secretase complex component Pen2 by Rer1

Christoph Kaether, Johanna Scheuermann, Matthias Fassler, Sonja Zilow, Keiro Shirotani, Christina Valkova, Bozidar Novak, Slavomir Kacmar, Harald Steiner, Christian Haass

EMBO Rep. 2007 Aug; 8(8): 743–748. Published online 2007 Jul 6. doi: 10.1038/sj.embor.7401027

PMCID:: PMC1978084

Abstract Article PDF–176K

Select item 55873205.

The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome

Hyo-Jin Park, Daniel Ryu, Mayur Parmar, Benoit I. Giasson, Nikolaus R. McFarland

PLoS One. 2017; 12(9): e0184262. Published online 2017 Sep 6. doi: 10.1371/journal.pone.0184262

PMCID:: PMC5587320

Abstract Article PDF–24M

Select item 42270136.

Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease

Taichi Hara, Yukiko Hashimoto, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Ken Sato

Sci Rep. 2014; 4: 6992. Published online 2014 Nov 11. doi: 10.1038/srep06992

PMCID:: PMC4227013

Abstract Article PDF–2.1M

Select item 35317367.

The Ubiquitin Ligase Synoviolin Up-regulates Amyloid β Production by Targeting a Negative Regulator of γ-Secretase, Rer1, for Degradation

Chiaki Tanabe, Tomoji Maeda, Kun Zou, Junjun Liu, Shuyu Liu, Toshihiro Nakajima, Hiroto Komano

J Biol Chem. 2012 Dec 28; 287(53): 44203–44211. Published online 2012 Nov 5. doi: 10.1074/jbc.M112.365296

PMCID:: PMC3531736

Abstract Article PDF–2.3M

Select item 36013488.

Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels

Nathalie Jurisch-Yaksi, Applonia J. Rose, Huiqi Lu, Tim Raemaekers, Sebastian Munck, Pieter Baatsen, Veerle Baert, Wendy Vermeire, Suzie J. Scales, Daphne Verleyen, Roel Vandepoel, Przemko Tylzanowski, Emre Yaksi, Thomy de Ravel, H. Joseph Yost, Guy Froyen, Cammon B. Arrington, Wim Annaert

J Cell Biol. 2013 Mar 18; 200(6): 709–720. doi: 10.1083/jcb.201208175

PMCID:: PMC3601348

Abstract Article PDF–11M

Select item 61598569.

Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development

Taichi Hara, Ikuko Maejima, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Satoshi Tsukamoto, Mika Tsunoda, Aguri Ono, Shota Yamakoshi, Satoshi Oikawa, Ken Sato

PLoS Genet. 2018 Sep; 14(9): e1007647. Published online 2018 Sep 27. doi: 10.1371/journal.pgen.1007647

PMCID:: PMC6159856

Abstract Article PDF–13M

Select item 676379110.

Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome

Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A. Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsak

Front Mol Neurosci. 2019; 12: 224. Published online 2019 Sep 20. doi: 10.3389/fnmol.2019.00224

PMCID:: PMC6763791

Abstract Article PDF–3.6M

Select item 432443911.

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

Jeffrey T. Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W. Chittenden, J. Wade Harper, Peter M. Howley

J Proteome Res. 2015 Feb 6; 14(2): 953–966. Published online 2014 Dec 4. doi: 10.1021/pr501005v

PMCID:: PMC4324439

Abstract Article PDF–7.5M

Select item 760717412.

Rho‐associated protein kinase‐dependent moesin phosphorylation is required for PD‐L1 stabilization in breast cancer

Fanbiao Meng, Yang Su, Bo Xu

Mol Oncol. 2020 Nov; 14(11): 2701–2712. Published online 2020 Oct 3. doi: 10.1002/1878-0261.12804

PMCID:: PMC7607174

Abstract Article PDF–4.2M

Select item 353489113.

SGTA recognizes a non-canonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote ER-associated degradation

Yue Xu, Mengli Cai, Yingying Yang, Lan Huang, Yihong Ye

Cell Rep. Author manuscript; available in PMC 2013 Jan 3.

Published in final edited form as: Cell Rep. 2012 Dec 27; 2(6): 1633–1644. Published online 2012 Dec 13. doi: 10.1016/j.celrep.2012.11.010

PMCID:: PMC3534891

Abstract Article PDF–3.0M

Select item 1094246714.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 901471115.

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach

Cell Rep. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030

PMCID:: PMC9014711

Abstract Article PDF–2.2M

Select item 408310616.

Proteomic Analysis of the Epidermal Growth Factor Receptor (EGFR) Interactome and Post-translational Modifications Associated with Receptor Endocytosis in Response to EGF and Stress

Jiefei Tong, Paul Taylor, Michael F. Moran

Mol Cell Proteomics. 2014 Jul; 13(7): 1644–1658. Published online 2014 May 5. doi: 10.1074/mcp.M114.038596

PMCID:: PMC4083106

Abstract Article PDF–2.6M

Select item 764232717.

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner

Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0

PMCID:: PMC7642327

Abstract Article PDF–12M

Select item 331091118.

Global landscape of HIV–human protein complexes

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Ivan D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2013 Jan 19.

Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 365–370. Published online 2011 Dec 21. doi: 10.1038/nature10719

PMCID:: PMC3310911

Abstract Article PDF–1.8M

Select item 612890519.

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability

Hema Adhikari, Christopher M. Counter

Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6

PMCID:: PMC6128905

Abstract Article PDF–2.2M

Select item 655126620.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Abstract Article PDF–3.4M

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