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Select item 27147641.

Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates

Nicoletta Scheller, Leonardo Bruno Mina, Rui Pedro Galão, Ashwin Chari, Mireia Giménez-Barcons, Amine Noueiry, Utz Fischer, Andreas Meyerhans, Juana Díez

Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32): 13517–13522. Published online 2009 Jul 23. doi: 10.1073/pnas.0906413106

PMCID:: PMC2714764

Abstract Article PDF–864K

Select item 49859322.

The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation

Marcos Arribas-Layton, Jaclyn Dennis, Eric J. Bennett, Christian K. Damgaard, Jens Lykke-Andersen

Mol Cell Biol. 2016 Sep 1; 36(17): 2226–2235. Prepublished online 2016 May 31. Published online 2016 Aug 12. doi: 10.1128/MCB.01102-15

PMCID:: PMC4985932

Abstract Article PDF–1.8M

Select item 40819523.

UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination

Friederike Hans, Fabienne C. Fiesel, Jennifer C. Strong, Sandra Jäckel, Tobias M. Rasse, Sven Geisler, Wolfdieter Springer, Jörg B. Schulz, Aaron Voigt, Philipp J. Kahle

J Biol Chem. 2014 Jul 4; 289(27): 19164–19179. Published online 2014 May 13. doi: 10.1074/jbc.M114.561704

PMCID:: PMC4081952

Abstract Article PDF–3.9M

Select item 13703554.

The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.

Dierk Ingelfinger, Donna J Arndt-Jovin, Reinhard Lührmann, Tilmann Achsel

RNA. 2002 Dec; 8(12): 1489–1501.

PMCID:: PMC1370355

Summary PDF–9.6M

Select item 11716455.

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

T Achsel, H Brahms, B Kastner, A Bachi, M Wilm, R Lührmann

EMBO J. 1999 Oct 15; 18(20): 5789–5802. doi: 10.1093/emboj/18.20.5789

PMCID:: PMC1171645

Summary PDF–613K

Select item 58816286.

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes

Tobias Brandmann, Hana Fakim, Zoya Padamsi, Ji‐Young Youn, Anne‐Claude Gingras, Marc R Fabian, Martin Jinek

EMBO J. 2018 Apr 3; 37(7): e97869. Published online 2018 Mar 6. doi: 10.15252/embj.201797869

PMCID:: PMC5881628

Abstract Article PDF–1.4M

Select item 11714247.

Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

J Salgado-Garrido, E Bragado-Nilsson, S Kandels-Lewis, B Séraphin

EMBO J. 1999 Jun 15; 18(12): 3451–3462. doi: 10.1093/emboj/18.12.3451

PMCID:: PMC1171424

Summary PDF–274K

Select item 65250988.

Mechanism of 5′ splice site transfer for human spliceosome activation

Clément Charenton, Max E. Wilkinson, Kiyoshi Nagai

Science. Author manuscript; available in PMC 2019 Oct 26.

Published in final edited form as: Science. 2019 Apr 26; 364(6438): 362–367. Published online 2019 Apr 11. doi: 10.1126/science.aax3289

PMCID:: PMC6525098

Abstract Article PDF–2.5M

Select item 56720369.

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly

Zhe Chen, Bin Gui, Yu Zhang, Guojia Xie, Wanjin Li, Shumeng Liu, Bosen Xu, Chongyang Wu, Lin He, Jianguo Yang, Xia Yi, Xiaohan Yang, Luyang Sun, Jing Liang, Yongfeng Shang

J Biol Chem. 2017 Nov 3; 292(44): 18113–18128. Published online 2017 Sep 6. doi: 10.1074/jbc.M117.797357

PMCID:: PMC5672036

Abstract Article PDF–2.9M

Select item 893369910.

Turnover of the mTOR inhibitor, DEPTOR, and downstream AKT phosphorylation in multiple myeloma cells, is dependent on ERK1-mediated phosphorylation

Mario Vega, Yu Chen, Yijiang Shi, Joseph Gera, Alan Lichtenstein

J Biol Chem. 2022 Apr; 298(4): 101750. Published online 2022 Feb 23. doi: 10.1016/j.jbc.2022.101750

PMCID:: PMC8933699

Abstract Article PDF–1.6M

Select item 534359311.

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor

Yuri Kotani, Daisuke Morito, Kenshiro Sakata, Shiori Ainuki, Munechika Sugihara, Tomohisa Hatta, Shun-ichiro Iemura, Seiji Takashima, Tohru Natsume, Kazuhiro Nagata

Sci Rep. 2017; 7: 44293. Published online 2017 Mar 9. doi: 10.1038/srep44293

PMCID:: PMC5343593

Abstract Article PDF–1.4M

Select item 471456112.

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II

Ryan P. McNamara, Jonathan E. Reeder, Elizabeth A. McMillan, Curtis W. Bacon, Jennifer L. McCann, Iván D’Orso

Mol Cell. Author manuscript; available in PMC 2017 Jan 7.

Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 39–53. Published online 2015 Dec 24. doi: 10.1016/j.molcel.2015.11.004

PMCID:: PMC4714561

Abstract Article PDF–2.2M

Select item 364706513.

The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells

Jesse L. Cox, Phillip J. Wilder, Joshua M. Gilmore, Erin L. Wuebben, Michael P. Washburn, Angie Rizzino

PLoS One. 2013; 8(5): e62857. Published online 2013 May 7. doi: 10.1371/journal.pone.0062857

PMCID:: PMC3647065

Abstract Article PDF–5.0M

Select item 584953414.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 44214715.

A Protein Interaction Framework for Human mRNA Degradation

Ben Lehner, Christopher M. Sanderson

Genome Res. 2004 Jul; 14(7): 1315–1323. doi: 10.1101/gr.2122004

PMCID:: PMC442147

Abstract Article PDF–272K

Select item 962912116.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 804593217.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 773761018.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 752655119.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

Select item 826661720.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

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